| Gene Symbol |
NME4
|
| Entrez Gene |
4833
|
| Alt Symbol |
NDPK-D, NM23H4, nm23-H4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NME/NM23 nucleoside diphosphate kinase 4
|
| Other Description |
NDK|NDP kinase D|NDP kinase, mitochondrial|NDPKD|non-metastatic cells 4, protein expressed in|nucleoside diphosphate kinase D|nucleoside diphosphate kinase, mitochondrial
|
| Swissprots |
Q5U0M9 O00746 A2IDD0
|
| Accessions |
AAK61230 EAW85817 EAW85818 EAW85819 EAW85820 O00746 AF086133 AK094439 BC004880 AAH04880 BC017067 AAH17067 BE266496 BG472605 BP328820 BQ650649 BQ932845 BT019438 AAV38245 CB143020 CF126980 HY182358 JF432627 ADZ15844 Y07604 CAA68877 NM_001286433 NP_001273362 NM_001286435 NP_001273364 NM_001286436 NP_001273365 NM_001286438 NP_001273367 NM_001286439 NP_001273368 NM_001286440 NP_001273369 NM_005009 NP_005000
|
| Function |
Major role in the synthesis of nucleoside triphosphates other than ATP. {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion intermembrane space.
|
| Tissue Specificity |
Widely distributed. Found at very high levels in prostate, heart, liver, small intestine, and skeletal muscle tissues, and in low amounts in the brain and in blood leukocytes.
|
| Top Pathways |
Purine metabolism, Pyrimidine metabolism
|
![Western Blot: NME4 Overexpression Lysate (Adult Normal) [NBL1-13686] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NME4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4734_NME4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13686-img0002.jpg)