Gene Symbol | NME4 |
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Entrez Gene | 4833 |
Alt Symbol | NDPK-D, NM23H4, nm23-H4 |
Species | Human |
Gene Type | protein-coding |
Description | NME/NM23 nucleoside diphosphate kinase 4 |
Other Description | NDK|NDP kinase D|NDP kinase, mitochondrial|NDPKD|non-metastatic cells 4, protein expressed in|nucleoside diphosphate kinase D|nucleoside diphosphate kinase, mitochondrial |
Swissprots | Q5U0M9 O00746 A2IDD0 |
Accessions | AAK61230 EAW85817 EAW85818 EAW85819 EAW85820 O00746 AF086133 AK094439 BC004880 AAH04880 BC017067 AAH17067 BE266496 BG472605 BP328820 BQ650649 BQ932845 BT019438 AAV38245 CB143020 CF126980 HY182358 JF432627 ADZ15844 Y07604 CAA68877 NM_001286433 NP_001273362 NM_001286435 NP_001273364 NM_001286436 NP_001273365 NM_001286438 NP_001273367 NM_001286439 NP_001273368 NM_001286440 NP_001273369 NM_005009 NP_005000 |
Function | Major role in the synthesis of nucleoside triphosphates other than ATP. {ECO:0000250}. |
Subcellular Location | Mitochondrion intermembrane space. |
Tissue Specificity | Widely distributed. Found at very high levels in prostate, heart, liver, small intestine, and skeletal muscle tissues, and in low amounts in the brain and in blood leukocytes. |
Top Pathways | Purine metabolism, Pyrimidine metabolism |
nm23-H4 CRISPR/Cas9 KO Plasmid (h) - sc-406017 from Santa Cruz Biotechnology
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nm23-H4 HDR Plasmid (h) - sc-406017-HDR from Santa Cruz Biotechnology
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nm23-H4 Double Nickase Plasmid (h) - sc-406017-NIC from Santa Cruz Biotechnology
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nm23-H4 Double Nickase Plasmid (h2) - sc-406017-NIC-2 from Santa Cruz Biotechnology
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nm23-H4 CRISPR Activation Plasmid (h) - sc-406017-ACT from Santa Cruz Biotechnology
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nm23-H4 CRISPR Activation Plasmid (h2) - sc-406017-ACT-2 from Santa Cruz Biotechnology
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nm23-H4 Lentiviral Activation Particles (h) - sc-406017-LAC from Santa Cruz Biotechnology
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nm23-H4 Lentiviral Activation Particles (h2) - sc-406017-LAC-2 from Santa Cruz Biotechnology
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nm23-H4 siRNA (h) - sc-61207 from Santa Cruz Biotechnology
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nm23-H4 shRNA Plasmid (h) - sc-61207-SH from Santa Cruz Biotechnology
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nm23-H4 shRNA (h) Lentiviral Particles - sc-61207-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU153301 from Sigma-Aldrich
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MISSION® esiRNA - EHU058601 from Sigma-Aldrich
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MISSION® siRNA - SIHK1430 from Sigma-Aldrich
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MISSION® siRNA - SIHK1429 from Sigma-Aldrich
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MISSION® siRNA - SIHK1431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15370 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15370 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03822 from Sigma-Aldrich
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NME4 siRNA (Human) - CRH3210 from Cohesion Biosciences
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NME4 RNAi - H00004833-R03 from Novus Biologicals
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shRNA set against Human NME4 (NM_005009.2) - SHH353172 from Creative biogene
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shRNA set against Human NME4(NM_005009.2) - SHR013926 from Creative biogene
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Human NME4 siRNA - orb263712 from Biorbyt
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NME4 shRNA Plasmid (Human) - CHH3210 from Cohesion Biosciences
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