| Gene Symbol | thraa |
|---|---|
| Entrez Gene | 30670 |
| Alt Symbol | TR[a]1, nr1a1, thra, thral, tra, tra1, wu:fb59g07 |
| Species | Zebrafish |
| Gene Type | protein-coding |
| Description | thyroid hormone receptor alpha a |
| Other Description | NR1A1-A|TRalpha-1|c-erbA|nuclear receptor subfamily 1 group A member 1-A|thyroid hormone receptor alpha 1|thyroid hormone receptor alpha-1|thyroid hormone receptor alpha-A|zTRalpha-A |
| Swissprots | Q4V9Q5 Q98867 A0ST47 |
| Accessions | AAB68762 AAB68763 Q98867 BC096778 AAH96778 BC164729 AAI64729 DQ991961 ABK64188 U54796 AAA99811 XM_005163985 XP_005164042 XM_005163986 XP_005164043 XM_009299514 XP_009297789 XM_009299515 XP_009297790 XM_009299516 XP_009297791 NM_131396 NP_571471 |
| Function | High affinity receptor for triiodothyronine (By similarity). In the absence of thyroid hormone during late blastula stage development, acts as a transcriptional repressor. Whereas in the presence of thyroid hormone, can act as an activator of transcription. In addition, represses retinoic acid (RA)-signaling during blastula and gastrula stages of development. {ECO:0000250, ECO:0000269|PubMed:17583703, ECO:0000269|PubMed:9447705}. |
| Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:9447705}. |
| Tissue Specificity | After the mid-blastula transition (MBT), expressed throughout the deep cells, which give rise to the embryo proper. In adults, isoform 2 shows highest expression in the eye and liver. Expressed in adult gonads. {ECO:0000269|PubMed:9447705}. |
| Top Pathways | Neuroactive ligand-receptor interaction |
Anti-Thyroid Hormone Receptor alpha Antibody - AC21-1263 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (AMCA) - AC21-1263-01 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (AP) - AC21-1263-02 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (APC) - AC21-1263-03 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (APC-Cy5.5) - AC21-1263-04 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (APC-Cy7) - AC21-1263-05 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (Avidin) - AC21-1263-06 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (Biotin) - AC21-1263-07 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (BPE) - AC21-1263-08 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (Cy3) - AC21-1263-09 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (Cy5) - AC21-1263-10 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (Cy5.5) - AC21-1263-11 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (FITC) - AC21-1263-12 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (Glucose Oxidase) - AC21-1263-13 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (HRP) - AC21-1263-14 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (PE-Cy5) - AC21-1263-15 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (PE-Cy5.5) - AC21-1263-16 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (PE-Cy7) - AC21-1263-17 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (PerCP) - AC21-1263-18 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (PerCP-Cy5.5) - AC21-1263-19 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (Rhodamine) - AC21-1263-20 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (RPE) - AC21-1263-21 from Abcore
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Anti-Thyroid Hormone Receptor alpha Antibody (Streptavidin) - AC21-1263-22 from Abcore
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Thyroid Hormone Receptor Antibody - 46-993 from ProSci
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Anti-Thra antibody - STJ71266 from St John's Laboratory Ltd
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