| Gene Symbol |
COX6B2
|
| Entrez Gene |
125965
|
| Alt Symbol |
COXVIB2, CT59
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
|
| Other Description |
COX VIb-2|cancer/testis antigen 59|cytochrome c oxidase subunit 6B2|cytochrome c oxidase subunit VIb, testes-specific
|
| Swissprots |
Q96DL5 Q6YFQ2 Q7L1R4
|
| Accessions |
EAW72367 EAW72368 Q6YFQ2 AK057427 BAB71481 AY152398 AAN46751 BC026123 AAH26123 BC064548 BC100899 AAI00900 BC100900 AAI00901 BC100901 AAI00902 BC100902 AAI00903 BG717038 HQ448609 ADQ33087 NM_144613 NP_653214
|
| Function |
Connects the two COX monomers into the physiological dimeric form. {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion intermembrane space {ECO:0000250}.
|
| Tissue Specificity |
Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines. {ECO:0000269|PubMed:12874793, ECO:0000269|PubMed:15905330}.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|
![Western Blot: COX6B2 Overexpression Lysate (Adult Normal) [NBL1-09417] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for COX6B2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8678_COX6B2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09417-img0002.jpg)