Gene Symbol | COX6B2 |
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Entrez Gene | 125965 |
Alt Symbol | COXVIB2, CT59 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome c oxidase subunit VIb polypeptide 2 (testis) |
Other Description | COX VIb-2|cancer/testis antigen 59|cytochrome c oxidase subunit 6B2|cytochrome c oxidase subunit VIb, testes-specific |
Swissprots | Q96DL5 Q6YFQ2 Q7L1R4 |
Accessions | EAW72367 EAW72368 Q6YFQ2 AK057427 BAB71481 AY152398 AAN46751 BC026123 AAH26123 BC064548 BC100899 AAI00900 BC100900 AAI00901 BC100901 AAI00902 BC100902 AAI00903 BG717038 HQ448609 ADQ33087 NM_144613 NP_653214 |
Function | Connects the two COX monomers into the physiological dimeric form. {ECO:0000250}. |
Subcellular Location | Mitochondrion intermembrane space {ECO:0000250}. |
Tissue Specificity | Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines. {ECO:0000269|PubMed:12874793, ECO:0000269|PubMed:15905330}. |
Top Pathways | Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
COX6b2 CRISPR/Cas9 KO Plasmid (h) - sc-414245 from Santa Cruz Biotechnology
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COX6b2 HDR Plasmid (h) - sc-414245-HDR from Santa Cruz Biotechnology
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COX6b2 Double Nickase Plasmid (h) - sc-414245-NIC from Santa Cruz Biotechnology
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COX6b2 Double Nickase Plasmid (h2) - sc-414245-NIC-2 from Santa Cruz Biotechnology
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COX6b2 CRISPR Activation Plasmid (h) - sc-414245-ACT from Santa Cruz Biotechnology
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COX6b2 CRISPR Activation Plasmid (h2) - sc-414245-ACT-2 from Santa Cruz Biotechnology
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COX6b2 Lentiviral Activation Particles (h) - sc-414245-LAC from Santa Cruz Biotechnology
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COX6b2 Lentiviral Activation Particles (h2) - sc-414245-LAC-2 from Santa Cruz Biotechnology
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COX6b2 siRNA (h) - sc-72984 from Santa Cruz Biotechnology
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COX6b2 shRNA Plasmid (h) - sc-72984-SH from Santa Cruz Biotechnology
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COX6b2 shRNA (h) Lentiviral Particles - sc-72984-V from Santa Cruz Biotechnology
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COX6B2 RNAi - H00125965-R01 from Novus Biologicals
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MISSION® esiRNA - EHU160581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6477 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6477 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07901 from Sigma-Aldrich
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COX6B2 siRNA (Human) - CRJ4823 from Cohesion Biosciences
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COX6B2 - MBS8216860 from MyBioSource
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shRNA set against Human COX6B2 (NM_144613.4) - SHH268341 from Creative biogene
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shRNA set against Human COX6B2(NM_144613.4) - SHG194779 from Creative biogene
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COX6B2 shRNA Plasmid (Human) - CHJ4823 from Cohesion Biosciences
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COX6B2 miRNA 3'UTR clone - MiUTR4H-TG02303 from Creative biogene
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