| Gene Symbol |
GRAP2
|
| Entrez Gene |
9402
|
| Alt Symbol |
GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL, GrbX, Grf40, Mona, P38
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GRB2-related adaptor protein 2
|
| Other Description |
GRB-2-like protein|GRB2-related adapter protein 2|GRB2-related protein with insert domain|SH3-SH2-SH3 adapter Mona|SH3-SH2-SH3 adaptor molecule|adapter protein GRID|grf-40|grf40 adapter protein|growth factor receptor-binding protein|growth factor receptor-bound protein 2-related adaptor protein 2|hematopoietic cell-associated adapter protein GrpL|hematopoietic cell-associated adaptor protein GRPL
|
| Swissprots |
O75791 Q9NRB7 O43726 B7Z8I3
|
| Accessions |
EAW60356 EAW60357 EAW60358 EAW60359 EAW60360 EAW60361 O75791 AF042380 AAC69273 AF090456 AAD13027 AF102694 AAD04926 AF121002 AAF31758 AF129476 AAD41782 AF236119 AAF60319 AF236120 AAF60320 AJ011736 CAA09757 AK303280 BAH13929 AK303332 BAH13944 AK303470 BAH13969 AK303512 BAH13978 AK303657 BAH14008 AK312830 BAG35685 AY069959 AAL58573 BC025692 AAH25692 BC026002 AAH26002 CR456498 CAG30384 CR536524 CAG38761 CR541849 CAG46647 CU013095 CAK54526 CU013383 CAK54825 DC409651 DQ893144 ABM84070 DQ896431 ABM87430 HY091328 Y18051 CAA77021 XM_006724376 XP_006724439 XM_011530515 XP_011528817 XM_011530516 XP_011528818 NM_001291824 NP_001278753 NM_001291825 NP_001278754 NM_001291826 NP_001278755 NM_001291828 NP_001278757 NM_004810 NP_004801
|
| Function |
Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:21179510}. Cytoplasm {ECO:0000269|PubMed:21179510}. Endosome {ECO:0000269|PubMed:21179510}.
|
| Top Pathways |
T cell receptor signaling pathway
|