PRKAB2

Gene Symbol	PRKAB2
Entrez Gene	5565
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	protein kinase, AMP-activated, beta 2 non-catalytic subunit
Other Description	5'-AMP-activated protein kinase subunit beta-2|5'-AMP-activated protein kinase, beta-2 subunit|AMP-activated protein kinase beta 2 non-catalytic subunit|AMPK beta 2|AMPK beta-2 chain|AMPK subunit beta-2
Swissprots	A8K9V5 B4DH06 Q5VXY0 O43741
Accessions	AAM74153 CAH72644 EAW50945 O43741 AI026131 AI638769 AJ224538 CAA12030 AK023717 AK292820 BAF85509 AK294863 BAG57967 AK304069 BAG64976 AK310982 AK316005 BAH14376 AK316183 BAH14554 AL037763 AU118301 AV646012 AV660341 BC053610 AAH53610 BM563523 BM724633 BM769516 BU166852 BU619639 BX478507 CA311731 CB111633 DA698245 HQ257946 ADR82700 KJ534919 AHW56559 KJ535024 AHW56663 KJ535025 AHW56664 XM_011509728 XP_011508030 XM_011509729 XP_011508031 NM_005399 NP_005390 NR_103870 NR_103871
Function	Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Top Pathways	Non-alcoholic fatty liver disease (NAFLD), Glucagon signaling pathway, AMPK signaling pathway, Oxytocin signaling pathway, Circadian rhythm

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AMPK beta 2 full length protein - ab137165 from Abcam Category Protein Prices $345.00 Sizes 100 µg Source E. coli Species Human

PRKAB2 / AMPK Beta 2 Antibody Blocking Peptide - LS-E20590 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRKAB2 / AMPK Beta 2 Antibody Blocking Peptide - LS-E20591 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRKAB2 / AMPK Beta 2 Antibody Blocking Peptide - LS-E8640 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AMPK beta 2/PRKAB2 Partial Recombinant Protein - H00005565-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

AMPK beta 2/PRKAB2 Recombinant Protein - H00005565-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human AMPK beta 2/PRKAB2 Protein - NBP2-23376 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

AMPK beta 2/PRKAB2 Peptide - P2143 from Novus Biologicals Category Peptide Species Human

AMPK-beta2-PRKAB2-Antibody-N-term-Blocking-peptide - BP7046a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AMPK beta 2 Protein - GTX111992-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

PRKAB2 Blocking Peptide - 33R-7854 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PRKAB2 protein (His tag) - 80R-2595 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

AMPK beta-2 chain / PRKAB2 (1-272, His-tag) - AR50641PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

AMPK beta-2 chain / PRKAB2 (1-272, His-tag) - AR50641PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

AMPK beta-2 chain / PRKAB2 - H00005565-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AMPK beta-2 chain / PRKAB2 - H00005565-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

AMPK beta-2 chain / PRKAB2 - H00005565-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AMPK beta-2 chain / PRKAB2 - H00005565-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PRKAB2, 1-272aa, Human, His tag, E.coli - 01-P1817 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

PRKAB2 fusion protein - Ag5806 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PRKAB2 fusion protein - ag6083 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

PRKAB2 Human - PKPS-053 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source E.coli. Species Human

Recombinant Human PRKAB2, GST-tagged - PRKAB2-1946H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human protein kinase, AMP-activated, beta 2 non-catalytic subunit, His-tagged - PRKAB2-378H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Protein Kinase, AMP Activated Beta 2 (PRKAb2) - RPG289Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

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