Gene Symbol |
MAD2L1BP
|
Entrez Gene |
9587
|
Alt Symbol |
CMT2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
MAD2L1 binding protein
|
Other Description |
MAD2L1-binding protein|caught by MAD2 protein
|
Swissprots |
B4DLV3 Q15013 Q6IBB1 E9PAT7
|
Accessions |
EAX04219 Q15013 AA883912 AK297172 BAG59665 AL537692 BC002904 AAH02904 BE297042 BI255998 BU845738 CB991410 CR456893 CAG33174 D14811 BAA03552 HQ447387 ADQ31873 NM_001003690 NP_001003690 NM_014628 NP_055443
|
Function |
May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. {ECO:0000269|PubMed:18022368}.
|
Subcellular Location |
Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
|