Gene Symbol | MAD2L1BP |
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Entrez Gene | 9587 |
Alt Symbol | CMT2 |
Species | Human |
Gene Type | protein-coding |
Description | MAD2L1 binding protein |
Other Description | MAD2L1-binding protein|caught by MAD2 protein |
Swissprots | B4DLV3 Q15013 Q6IBB1 E9PAT7 |
Accessions | EAX04219 Q15013 AA883912 AK297172 BAG59665 AL537692 BC002904 AAH02904 BE297042 BI255998 BU845738 CB991410 CR456893 CAG33174 D14811 BAA03552 HQ447387 ADQ31873 NM_001003690 NP_001003690 NM_014628 NP_055443 |
Function | May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. {ECO:0000269|PubMed:18022368}. |
Subcellular Location | Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle. |
MAD2L1BP CRISPR/Cas9 KO Plasmid (h) - sc-404889 from Santa Cruz Biotechnology
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MAD2L1BP HDR Plasmid (h) - sc-404889-HDR from Santa Cruz Biotechnology
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MAD2L1BP Double Nickase Plasmid (h) - sc-404889-NIC from Santa Cruz Biotechnology
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MAD2L1BP Double Nickase Plasmid (h2) - sc-404889-NIC-2 from Santa Cruz Biotechnology
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MAD2L1BP CRISPR Activation Plasmid (h) - sc-404889-ACT from Santa Cruz Biotechnology
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MAD2L1BP CRISPR Activation Plasmid (h2) - sc-404889-ACT-2 from Santa Cruz Biotechnology
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MAD2L1BP Lentiviral Activation Particles (h) - sc-404889-LAC from Santa Cruz Biotechnology
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MAD2L1BP Lentiviral Activation Particles (h2) - sc-404889-LAC-2 from Santa Cruz Biotechnology
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MAD2L1BP siRNA (h) - sc-95335 from Santa Cruz Biotechnology
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MAD2L1BP shRNA Plasmid (h) - sc-95335-SH from Santa Cruz Biotechnology
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MAD2L1BP shRNA (h) Lentiviral Particles - sc-95335-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU047101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12894 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12894 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03691 from Sigma-Aldrich
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MAD2L1BP siRNA (Human) - CRH6381 from Cohesion Biosciences
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shRNA set against Human MAD2 (NM_014628.2) - SHH336507 from Creative biogene
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shRNA set against Human MAD2L1BP(NM_014628.2) - SHH169823 from Creative biogene
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shRNA set against Human MAD2L1BP(NM_001003690.1) - SHH169859 from Creative biogene
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MAD2L1BP shRNA Plasmid (Human) - CHH6381 from Cohesion Biosciences
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MAD2L1BP miRNA 3'UTR clone - MiUTR1H-05993 from Creative biogene
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MAD2L1BP miRNA 3'UTR clone - MiUTR1H-05994 from Creative biogene
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