| Gene Symbol |
APOA1BP
|
| Entrez Gene |
128240
|
| Alt Symbol |
AIBP, YJEFN1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
apolipoprotein A-I binding protein
|
| Other Description |
AI-BP|NAD(P)H-hydrate epimerase|NAD(P)HX epimerase|apoA-I binding protein|apolipoprotein A-I-binding protein|yjeF N-terminal domain-containing protein 1|yjeF_N1
|
| Swissprots |
B4DGY3 Q496C6 Q8NCW5 Q5T3I2
|
| Accessions |
EAW52941 EAW52942 EAW52943 Q8NCW5 AJ315849 CAC86580 AK294835 BAG57944 AK298222 BAG60492 AK316083 BAH14454 BC056917 AAH56917 BC100931 AAI00932 BC100932 AAI00933 BC100933 AAI00934 BC100934 AAI00935 BG723681 BQ430064 NM_144772 NP_658985
|
| Function |
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. {ECO:0000255|HAMAP-Rule:MF_03159}.
|
| Subcellular Location |
Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03159}. Secreted {ECO:0000255|HAMAP-Rule:MF_03159, ECO:0000269|PubMed:11991719}. Note=In sperm, secretion gradually increases during capacitation. {ECO:0000255|HAMAP-Rule:MF_03159}.
|
| Tissue Specificity |
Ubiquitously expressed, with highest levels in kidney, heart and liver. Present in cerebrospinal fluid and urine but not in serum from healthy patients. Present in serum of sepsis patients (at protein level). {ECO:0000269|PubMed:11991719}.
|
![Western Blot: APOA1BP Overexpression Lysate (Adult Normal) [NBP2-05519] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for APOA1BP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10653_APOA1BP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05519-img0001.jpg)