CBR1

Gene Symbol CBR1
Entrez Gene 873
Alt Symbol CBR, SDR21C1, hCBR1
Species Human
Gene Type protein-coding
Description carbonyl reductase 1
Other Description 15-hydroxyprostaglandin dehydrogenase|NADPH-dependent carbonyl reductase 1|carbonyl reductase (NADPH) 1|carbonyl reductase [NADPH] 1|prostaglandin 9-ketoreductase|prostaglandin-E(2) 9-reductase|short chain dehydrogenase/reductase family 21C member 1|short chain dehydrogenase/reductase family 21C, member 1
Swissprots Q3LHW8 B2RBZ7 B4DFK7 P16152
Accessions AAA17881 ABK97430 BAA33498 BAA89424 BAA95508 EAX09752 EAX09753 EAX09754 EAX09755 P16152 AB124848 BAE45940 AK294142 BAG57468 AK308691 AK311219 AK314879 BAG37394 AL548852 BC002511 AAH02511 BC015640 AAH15640 BT019843 AAV38646 CR541708 CAG46509 DQ892353 ABM83279 DQ895559 ABM86485 J04056 AAA52070 N51716 NM_001286789 NP_001273718 NM_001757 NP_001748
Function NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. {ECO:0000269|PubMed:15799708, ECO:0000269|PubMed:17912391, ECO:0000269|PubMed:18449627, ECO:0000269|PubMed:18826943}.
Subcellular Location Cytoplasm.
Top Pathways Chemical carcinogenesis, Arachidonic acid metabolism, Metabolism of xenobiotics by cytochrome P450

Carbonyl reductase [NADPH] 1 (CBR1/CBR/CRN), Human, ELISA Kit - CSB-E17009h from ARP American Research Products

Category ELISA Kit
Prices $550.00, $790.00, $791.00, $794.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Carbonyl reductase [NADPH] 1 (CBR1/CBR/CRN), Human, ELISA Kit - E01C1411 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

CBR1 (Human) IP-WB Antibody Pair - H00000873-PW2 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

CBR1 (Human) Matched Antibody Pair - H00000873-AP11 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

Carbonyl reductase [NADPH] 1 (CBR1/CBR/CRN), ELISA Kit - MBS7201140 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbonyl reductase (NADPH) 1 (CBR1/CBR/CRN), ELISA Kit - MBS7207230 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbonyl reductase (NADPH) 3 (CBR3), ELISA Kit - MBS7231605 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

carbonyl reductase 1, ELISA Kit - MBS705832 from MyBioSource

Category ELISA Kit
Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 7.81 pg/ml.
Range 31.25 pg/ml -2000 pg/ml.

Human Carbonyl reductase [NADPH] 1 (CBR1/CBR/CRN) ELISA kit - CSB-E17009h from Cusabio

Category ELISA Kit
Sensitivity 7.81pg/ml
Range 31.25 pg/ml-2000 pg/ml

Human Carbonyl reductase [NADPH] 1 (CBR1/CBR/CRN) ELISA Kit - EKC32988 from Biomatik

Category ELISA Kit
Prices $795.00, $3,021.00, $5,645.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 7.81 pg/ml
Range 31.25 pg/ml-2000 pg/ml

Human CBR1 ELISA Kit - E006538 from Biobool

Category ELISA Kit
Sensitivity 7.81 pg/ml.

anti-CBR1 antibody - ARG54109 from Arigo Biolaboratories

Category ELISA Kit

anti-CBR1 antibody - ARG63277 from Arigo Biolaboratories

Category ELISA Kit

CBR1 ELISA Kit (Human) (OKCA01143) - OKCA01143 from Aviva Systems Biology

Category ELISA Kit
Prices $665.00
Sizes 96 wells
Sensitivity 7.81 pg/mL
Range 31.25 - 2,000 pg/mL

Human CBR1 ELISA Kit - orb407153 from Biorbyt

Category ELISA Kit
Sensitivity 7.81pg/ml
Range 31.25 pg/ml-2000 pg/ml
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