| Gene Symbol |
ANKRD13A
|
| Entrez Gene |
88455
|
| Alt Symbol |
ANKRD13, NY-REN-25
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ankyrin repeat domain 13A
|
| Other Description |
NY-REN-25 antigen|ankyrin repeat domain-containing protein 13A
|
| Swissprots |
O60736 Q8IZ07
|
| Accessions |
EAW97891 EAW97892 EAW97893 Q8IZ07 AF064604 AAC17109 AF155103 AAD42869 AK022658 BAG51101 AK025261 AK095130 BAG52990 AK130522 AK293232 BAG56771 AK302535 BAG63807 AK308923 AY364251 AAQ76810 BC032833 AAH32833 BC057817 LK938784 XM_005253980 XP_005254037 XM_005253981 XP_005254038 XM_005253982 XP_005254039 XM_005253984 XP_005254041 XM_011538937 XP_011537239 XM_011538938 XP_011537240 XR_944812 NM_033121 NP_149112
|
| Function |
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand- activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. {ECO:0000269|PubMed:22298428}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:22298428}. Late endosome {ECO:0000269|PubMed:22298428}. Note=Interaction with EGFR may enhance association with the cell membrane.
|