Gene Symbol | ANKRD13A |
---|---|
Entrez Gene | 88455 |
Alt Symbol | ANKRD13, NY-REN-25 |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat domain 13A |
Other Description | NY-REN-25 antigen|ankyrin repeat domain-containing protein 13A |
Swissprots | O60736 Q8IZ07 |
Accessions | EAW97891 EAW97892 EAW97893 Q8IZ07 AF064604 AAC17109 AF155103 AAD42869 AK022658 BAG51101 AK025261 AK095130 BAG52990 AK130522 AK293232 BAG56771 AK302535 BAG63807 AK308923 AY364251 AAQ76810 BC032833 AAH32833 BC057817 LK938784 XM_005253980 XP_005254037 XM_005253981 XP_005254038 XM_005253982 XP_005254039 XM_005253984 XP_005254041 XM_011538937 XP_011537239 XM_011538938 XP_011537240 XR_944812 NM_033121 NP_149112 |
Function | Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand- activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. {ECO:0000269|PubMed:22298428}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:22298428}. Late endosome {ECO:0000269|PubMed:22298428}. Note=Interaction with EGFR may enhance association with the cell membrane. |
ANKRD13A CRISPR/Cas9 KO Plasmid (h) - sc-413795 from Santa Cruz Biotechnology
|
||||||||
ANKRD13A HDR Plasmid (h) - sc-413795-HDR from Santa Cruz Biotechnology
|
||||||||
ANKRD13A Double Nickase Plasmid (h) - sc-413795-NIC from Santa Cruz Biotechnology
|
||||||||
ANKRD13A Double Nickase Plasmid (h2) - sc-413795-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ANKRD13A CRISPR Activation Plasmid (h) - sc-413795-ACT from Santa Cruz Biotechnology
|
||||||||
ANKRD13A CRISPR Activation Plasmid (h2) - sc-413795-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ANKRD13A Lentiviral Activation Particles (h) - sc-413795-LAC from Santa Cruz Biotechnology
|
||||||||
ANKRD13A Lentiviral Activation Particles (h2) - sc-413795-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ANKRD13A siRNA (h) - sc-95950 from Santa Cruz Biotechnology
|
||||||||
ANKRD13A shRNA Plasmid (h) - sc-95950-SH from Santa Cruz Biotechnology
|
||||||||
ANKRD13A shRNA (h) Lentiviral Particles - sc-95950-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU062321 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3175 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3175 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR10559 from Sigma-Aldrich
|
||||||||
ANKRD13A siRNA (Human) - CRJ3846 from Cohesion Biosciences
|
||||||||
ANKRD13A - MBS8210656 from MyBioSource
|
||||||||
shRNA set against Human Ankrd13a (NM_033121.1) - SHH236574 from Creative biogene
|
||||||||
shRNA set against Human ANKRD13A(NM_033121.1) - SHG059545 from Creative biogene
|
||||||||
Human ANKRD13A siRNA - orb274347 from Biorbyt
|
||||||||
ANKRD13A shRNA Plasmid (Human) - CHJ3846 from Cohesion Biosciences
|
||||||||
ANKRD13A miRNA 3'UTR clone - MiUTR1H-00380 from Creative biogene
|