Gene Symbol | DNAJC24 |
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Entrez Gene | 120526 |
Alt Symbol | DPH4, JJJ3, ZCSL3 |
Species | Human |
Gene Type | protein-coding |
Description | DnaJ (Hsp40) homolog, subfamily C, member 24 |
Other Description | 1700030A21Rik|CSL-type zinc finger-containing protein 3|DPH4 homolog (JJJ3, S. cerevisiae)|DPH4, JJJ3 homolog|diphthamide biosynthesis protein 4|dnaJ homolog subfamily C member 24|zinc finger, CSL domain containing 3|zinc finger, CSL-type containing 3 |
Swissprots | A8K0V0 I6L9B4 B1ALC1 Q6P3W2 |
Accessions | EAW68241 EAW68242 EAW68243 EAW68244 EAW68245 EAW68246 EAW68247 Q6P3W2 AK123087 AK289665 BAF82354 AL050199 AL833128 BC036571 AAH36571 BC044931 BC063804 AAH63804 CD685768 XR_930844 NM_181706 NP_859057 |
Function | Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron- bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta). {ECO:0000269|PubMed:22367199, ECO:0000269|PubMed:22509046}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. |
ZCSL3 CRISPR/Cas9 KO Plasmid (h) - sc-417461 from Santa Cruz Biotechnology
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ZCSL3 HDR Plasmid (h) - sc-417461-HDR from Santa Cruz Biotechnology
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ZCSL3 Double Nickase Plasmid (h) - sc-417461-NIC from Santa Cruz Biotechnology
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ZCSL3 Double Nickase Plasmid (h2) - sc-417461-NIC-2 from Santa Cruz Biotechnology
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ZCSL3 CRISPR Activation Plasmid (h) - sc-417461-ACT from Santa Cruz Biotechnology
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ZCSL3 CRISPR Activation Plasmid (h2) - sc-417461-ACT-2 from Santa Cruz Biotechnology
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ZCSL3 Lentiviral Activation Particles (h) - sc-417461-LAC from Santa Cruz Biotechnology
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ZCSL3 Lentiviral Activation Particles (h2) - sc-417461-LAC-2 from Santa Cruz Biotechnology
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ZCSL3 siRNA (h) - sc-63237 from Santa Cruz Biotechnology
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ZCSL3 shRNA Plasmid (h) - sc-63237-SH from Santa Cruz Biotechnology
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ZCSL3 shRNA (h) Lentiviral Particles - sc-63237-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU034391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7371 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11458 from Sigma-Aldrich
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DNAJC24 siRNA (Human) - CRJ4644 from Cohesion Biosciences
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DNAJC24 - MBS8206861 from MyBioSource
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shRNA set against Human DNAJC24 (NM_181706.4) - SHH279581 from Creative biogene
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shRNA set against Human DPH4(NM_181706.4) - SHG209007 from Creative biogene
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Human DNAJC24 siRNA - orb275145 from Biorbyt
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DNAJC24 shRNA Plasmid (Human) - CHJ4644 from Cohesion Biosciences
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DNAJC24 miRNA 3'UTR clone - MiUTR1H-02967 from Creative biogene
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