Gene Symbol | PCK1 |
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Entrez Gene | 5105 |
Alt Symbol | PEPCK-C, PEPCK1, PEPCKC |
Species | Human |
Gene Type | protein-coding |
Description | phosphoenolpyruvate carboxykinase 1 (soluble) |
Other Description | PEP carboxykinase|phosphoenolpyruvate carboxykinase, cytosolic|phosphoenolpyruvate carboxykinase, cytosolic [GTP]|phosphoenolpyruvate carboxylase|phosphopyruvate carboxylase |
Swissprots | Q8TCA3 A8K437 Q9UJD2 P35558 B4DT64 |
Accessions | AAA02558 AAA91026 AAV50001 EAW75514 EAW75515 P35558 AI635748 AK290802 BAF83491 AK300072 BAG61876 AK303806 BAG64760 AW007566 BC023978 AAH23978 BJ993061 BM758256 BM768055 BX648510 DB187814 DQ893518 ABM84444 DQ896497 ABM87496 L05144 AAA60084 XM_011528839 XP_011527141 NM_002591 NP_002582 |
Function | Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Major sites of expression are liver, kidney and adipocytes. |
Top Pathways | Glucagon signaling pathway, Glycolysis / Gluconeogenesis, AMPK signaling pathway, PI3K-Akt signaling pathway, Proximal tubule bicarbonate reclamation |
Human PCK1 full length protein - ab114362 from Abcam
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Human PCK1 full length protein - ab119469 from Abcam
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Human PCK1 peptide - ab86626 from Abcam
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Human PCK1 peptide - ab87372 from Abcam
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PCK1 Antibody Blocking Peptide - LS-E11546 from LifeSpan Bioscience
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PCK1 Antibody Blocking Peptide - LS-E11547 from LifeSpan Bioscience
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PCK1 Antibody Blocking Peptide - LS-E26323 from LifeSpan Bioscience
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PCK1 Antibody Blocking Peptide - LS-E25955 from LifeSpan Bioscience
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PCK1 Antibody Blocking Peptide - LS-E9490 from LifeSpan Bioscience
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PCK1 Recombinant Protein - H00005105-P01 from Novus Biologicals
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Recombinant Human PCK1 Protein - NBP1-78871 from Novus Biologicals
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PCK1 Peptide - P3098 from Novus Biologicals
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PCK1 Peptide - P3097 from Novus Biologicals
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PCK1-Antibody-C-term-Blocking-Peptide - BP8093b from Abgent, a WuXi AppTec company
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PCK1-Antibody-N-term-Blocking-Peptide - BP8093a from Abgent, a WuXi AppTec company
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PCK1 (internal region) blocking peptide - GTX89064-PEP from GeneTex
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PCK1 (internal) blocking peptide - GTX89406-PEP from GeneTex
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Recombinant human Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (OPCA00178) - OPCA00178 from Aviva Systems Biology
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Recombinant E.coli Phosphoenolpyruvate carboxylase (OPCA01177) - OPCA01177 from Aviva Systems Biology
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Human PCK1 PEPCK1 protein - orb244430 from Biorbyt
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Human PCK1 protein - orb168996 from Biorbyt
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Goat anti PCK1 antibody Immunizing peptide - orb17935 from Biorbyt
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PCK1 Immunizing peptide - orb17599 from Biorbyt
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PCK1 Blocking Peptide - 33R-6700 from Fitzgerald
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PCK1 Blocking Peptide - 33R-7272 from Fitzgerald
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