PCK1

Gene Symbol PCK1
Entrez Gene 5105
Alt Symbol PEPCK-C, PEPCK1, PEPCKC
Species Human
Gene Type protein-coding
Description phosphoenolpyruvate carboxykinase 1 (soluble)
Other Description PEP carboxykinase|phosphoenolpyruvate carboxykinase, cytosolic|phosphoenolpyruvate carboxykinase, cytosolic [GTP]|phosphoenolpyruvate carboxylase|phosphopyruvate carboxylase
Swissprots Q8TCA3 A8K437 Q9UJD2 P35558 B4DT64
Accessions AAA02558 AAA91026 AAV50001 EAW75514 EAW75515 P35558 AI635748 AK290802 BAF83491 AK300072 BAG61876 AK303806 BAG64760 AW007566 BC023978 AAH23978 BJ993061 BM758256 BM768055 BX648510 DB187814 DQ893518 ABM84444 DQ896497 ABM87496 L05144 AAA60084 XM_011528839 XP_011527141 NM_002591 NP_002582
Function Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
Subcellular Location Cytoplasm.
Tissue Specificity Major sites of expression are liver, kidney and adipocytes.
Top Pathways Glucagon signaling pathway, Glycolysis / Gluconeogenesis, AMPK signaling pathway, PI3K-Akt signaling pathway, Proximal tubule bicarbonate reclamation

PEPCK-C CRISPR/Cas9 KO Plasmid (h) - sc-401295 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEPCK-C HDR Plasmid (h) - sc-401295-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEPCK-C Double Nickase Plasmid (h) - sc-401295-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEPCK-C Double Nickase Plasmid (h2) - sc-401295-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEPCK-C CRISPR Activation Plasmid (h) - sc-401295-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEPCK-C CRISPR Activation Plasmid (h2) - sc-401295-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEPCK-C Lentiviral Activation Particles (h) - sc-401295-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEPCK-C Lentiviral Activation Particles (h2) - sc-401295-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEPCK-C siRNA (h) - sc-76106 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PEPCK-C shRNA Plasmid (h) - sc-76106-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PEPCK-C shRNA (h) Lentiviral Particles - sc-76106-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PCK1 RNAi - H00005105-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU049291 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® siRNA - SIHK1531 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1529 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1530 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN16478 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16478 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PCK1 siRNA (Human) - CRH3397 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PCK1 (NM_002591.3) - SHH371860 from Creative biogene

Category siRNA
Species Reactivities Human

PCK1 shRNA Plasmid (Human) - CHH3397 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PCK1 miRNA 3'UTR clone - MiUTR3H-13160 from Creative biogene

Species Reactivities Human
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