| Gene Symbol |
ZNF473
|
| Entrez Gene |
25888
|
| Alt Symbol |
HZFP100, ZN473
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger protein 473
|
| Other Description |
zfp-100|zinc finger protein 100 homolog|zinc finger protein ZFP100
|
| Swissprots |
Q8WTR7 Q9Y4Q7 Q9ULS9 A8K8T7
|
| Accessions |
EAW52593 EAW52594 Q8WTR7 AB032967 BAA86455 AF454744 AAL51029 AK054671 AK292452 BAF85141 AK302293 BAG63633 AL080143 CAB45736 BC018612 AAH18612 BX492803 BX648093 CAH56173 DB086543 EU446788 ABZ92317 JF432323 ADZ15540 XM_011526707 XP_011525009 NM_001006656 NP_001006657 NM_001308424 NP_001295353 NM_015428 NP_056243
|
| Function |
Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases. {ECO:0000269|PubMed:11782445, ECO:0000269|PubMed:16714279, ECO:0000269|PubMed:16914750}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:16714279}. Note=Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA.
|