Gene Symbol | ZNF473 |
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Entrez Gene | 25888 |
Alt Symbol | HZFP100, ZN473 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 473 |
Other Description | zfp-100|zinc finger protein 100 homolog|zinc finger protein ZFP100 |
Swissprots | Q8WTR7 Q9Y4Q7 Q9ULS9 A8K8T7 |
Accessions | EAW52593 EAW52594 Q8WTR7 AB032967 BAA86455 AF454744 AAL51029 AK054671 AK292452 BAF85141 AK302293 BAG63633 AL080143 CAB45736 BC018612 AAH18612 BX492803 BX648093 CAH56173 DB086543 EU446788 ABZ92317 JF432323 ADZ15540 XM_011526707 XP_011525009 NM_001006656 NP_001006657 NM_001308424 NP_001295353 NM_015428 NP_056243 |
Function | Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases. {ECO:0000269|PubMed:11782445, ECO:0000269|PubMed:16714279, ECO:0000269|PubMed:16914750}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16714279}. Note=Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA. |
ZFP100 CRISPR/Cas9 KO Plasmid (h) - sc-411821 from Santa Cruz Biotechnology
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ZFP100 HDR Plasmid (h) - sc-411821-HDR from Santa Cruz Biotechnology
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ZFP100 Double Nickase Plasmid (h) - sc-411821-NIC from Santa Cruz Biotechnology
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ZFP100 Double Nickase Plasmid (h2) - sc-411821-NIC-2 from Santa Cruz Biotechnology
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ZFP100 CRISPR Activation Plasmid (h) - sc-411821-ACT from Santa Cruz Biotechnology
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ZFP100 CRISPR Activation Plasmid (h2) - sc-411821-ACT-2 from Santa Cruz Biotechnology
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ZFP100 Lentiviral Activation Particles (h) - sc-411821-LAC from Santa Cruz Biotechnology
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ZFP100 Lentiviral Activation Particles (h2) - sc-411821-LAC-2 from Santa Cruz Biotechnology
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ZFP100 siRNA (h) - sc-97520 from Santa Cruz Biotechnology
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ZFP100 shRNA Plasmid (h) - sc-97520-SH from Santa Cruz Biotechnology
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ZFP100 shRNA (h) Lentiviral Particles - sc-97520-V from Santa Cruz Biotechnology
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ZNF473 RNAi - H00025888-R01 from Novus Biologicals
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ZNF473 RNAi - H00025888-R02 from Novus Biologicals
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MISSION® esiRNA - EHU032261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23477 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23477 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10026 from Sigma-Aldrich
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ZNF473 siRNA (Human) - CRH8565 from Cohesion Biosciences
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ZNF473 - MBS8212277 from MyBioSource
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shRNA set against Human ZNF473 (NM_001006656.1) - SHH454040 from Creative biogene
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Human ZNF473 siRNA - orb269067 from Biorbyt
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ZNF473 shRNA Plasmid (Human) - CHH8565 from Cohesion Biosciences
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ZNF473 miRNA 3'UTR clone - MiUTR1H-11616 from Creative biogene
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ZNF473 miRNA 3'UTR clone - MiUTR3H-16743 from Creative biogene
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