| Gene Symbol |
AKAP11
|
| Entrez Gene |
11215
|
| Alt Symbol |
AKAP-11, AKAP220, PPP1R44, PRKA11
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
A kinase (PRKA) anchor protein 11
|
| Other Description |
A-kinase anchor protein 11|A-kinase anchor protein 220 kDa|A-kinase anchoring protein, 220kDa|a kinase anchor protein 220 kDa|protein kinase A anchoring protein 11|protein kinase A-anchoring protein 11|protein phosphatase 1, regulatory subunit 44
|
| Swissprots |
O75124 Q9UKA4 Q9NUK7
|
| Accessions |
EAX08676 EAX08677 Q9UKA4 AB014529 BAA31604 AF176555 AAF07045 AK002166 BAA92117 AK074384 BC156135 AAI56136 BC172498 AAI72498 BE670178 BE694434 CR627087 CAH10362 DA780016 XM_005266247 XP_005266304 XM_005266248 XP_005266305 XM_005266249 XP_005266306 XM_005266250 XP_005266307 XM_011534903 XP_011533205 XM_011534904 XP_011533206 XM_011534905 XP_011533207 XM_011534906 XP_011533208 NM_016248 NP_057332 NM_144490
|
| Function |
Binds to type II regulatory subunits of protein kinase A and anchors/targets them.
|
| Subcellular Location |
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic in premeiotic pachytene spermatocytes and in the centrosome of developing postmeiotic germ cells, while a midpiece/centrosome localization was found in elongating spermatocytes and mature sperm.
|
| Tissue Specificity |
Expressed in heart, brain, lung, liver, kidney, testis and ovary. Weakly expressed in skeletal muscle, pancreas and spleen.
|