Gene Symbol | AKAP11 |
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Entrez Gene | 11215 |
Alt Symbol | AKAP-11, AKAP220, PPP1R44, PRKA11 |
Species | Human |
Gene Type | protein-coding |
Description | A kinase (PRKA) anchor protein 11 |
Other Description | A-kinase anchor protein 11|A-kinase anchor protein 220 kDa|A-kinase anchoring protein, 220kDa|a kinase anchor protein 220 kDa|protein kinase A anchoring protein 11|protein kinase A-anchoring protein 11|protein phosphatase 1, regulatory subunit 44 |
Swissprots | O75124 Q9UKA4 Q9NUK7 |
Accessions | EAX08676 EAX08677 Q9UKA4 AB014529 BAA31604 AF176555 AAF07045 AK002166 BAA92117 AK074384 BC156135 AAI56136 BC172498 AAI72498 BE670178 BE694434 CR627087 CAH10362 DA780016 XM_005266247 XP_005266304 XM_005266248 XP_005266305 XM_005266249 XP_005266306 XM_005266250 XP_005266307 XM_011534903 XP_011533205 XM_011534904 XP_011533206 XM_011534905 XP_011533207 XM_011534906 XP_011533208 NM_016248 NP_057332 NM_144490 |
Function | Binds to type II regulatory subunits of protein kinase A and anchors/targets them. |
Subcellular Location | Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic in premeiotic pachytene spermatocytes and in the centrosome of developing postmeiotic germ cells, while a midpiece/centrosome localization was found in elongating spermatocytes and mature sperm. |
Tissue Specificity | Expressed in heart, brain, lung, liver, kidney, testis and ovary. Weakly expressed in skeletal muscle, pancreas and spleen. |
AKAP 220 CRISPR/Cas9 KO Plasmid (h) - sc-405585 from Santa Cruz Biotechnology
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AKAP 220 HDR Plasmid (h) - sc-405585-HDR from Santa Cruz Biotechnology
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AKAP 220 Double Nickase Plasmid (h) - sc-405585-NIC from Santa Cruz Biotechnology
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AKAP 220 Double Nickase Plasmid (h2) - sc-405585-NIC-2 from Santa Cruz Biotechnology
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AKAP 220 CRISPR Activation Plasmid (h) - sc-405585-ACT from Santa Cruz Biotechnology
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AKAP 220 CRISPR Activation Plasmid (h2) - sc-405585-ACT-2 from Santa Cruz Biotechnology
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AKAP 220 Lentiviral Activation Particles (h) - sc-405585-LAC from Santa Cruz Biotechnology
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AKAP 220 Lentiviral Activation Particles (h2) - sc-405585-LAC-2 from Santa Cruz Biotechnology
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AKAP 220 siRNA (h) - sc-105049 from Santa Cruz Biotechnology
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AKAP 220 shRNA Plasmid (h) - sc-105049-SH from Santa Cruz Biotechnology
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AKAP 220 shRNA (h) Lentiviral Particles - sc-105049-V from Santa Cruz Biotechnology
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AKAP11 RNAi - H00011215-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN3003 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3003 from Sigma-Aldrich
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AKAP11 siRNA (Human) - CRH7684 from Cohesion Biosciences
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AKAP11 - MBS8211459 from MyBioSource
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shRNA set against Human AKAP11 (NM_016248.3) - SHH234186 from Creative biogene
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Human AKAP11 siRNA - orb268186 from Biorbyt
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AKAP11 shRNA Plasmid (Human) - CHH7684 from Cohesion Biosciences
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AKAP11 miRNA 3'UTR clone - MiUTR4H-TG00245 from Creative biogene
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