Gene Symbol |
TXNDC17
|
Entrez Gene |
84817
|
Alt Symbol |
TRP14, TXNL5
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
thioredoxin domain containing 17
|
Other Description |
14 kDa thioredoxin-related protein|protein 42-9-9|thioredoxin (Trx)-related protein, 14 kDa|thioredoxin domain-containing protein 17|thioredoxin-like 5|thioredoxin-like protein 5
|
Swissprots |
A8K7E8 Q9BRA2
|
Accessions |
EAW90302 Q9BRA2 AF086210 AJ344101 CAC51435 AK291963 BAF84652 AK311853 BC006405 AAH06405 BC050406 CA431010 NM_032731 NP_116120
|
Function |
Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. {ECO:0000269|PubMed:14607843, ECO:0000269|PubMed:14607844}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:14607844}.
|
Tissue Specificity |
Ubiquitously expressed in cell lines. {ECO:0000269|PubMed:14607844}.
|