Gene Symbol | TXNDC17 |
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Entrez Gene | 84817 |
Alt Symbol | TRP14, TXNL5 |
Species | Human |
Gene Type | protein-coding |
Description | thioredoxin domain containing 17 |
Other Description | 14 kDa thioredoxin-related protein|protein 42-9-9|thioredoxin (Trx)-related protein, 14 kDa|thioredoxin domain-containing protein 17|thioredoxin-like 5|thioredoxin-like protein 5 |
Swissprots | A8K7E8 Q9BRA2 |
Accessions | EAW90302 Q9BRA2 AF086210 AJ344101 CAC51435 AK291963 BAF84652 AK311853 BC006405 AAH06405 BC050406 CA431010 NM_032731 NP_116120 |
Function | Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. {ECO:0000269|PubMed:14607843, ECO:0000269|PubMed:14607844}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14607844}. |
Tissue Specificity | Ubiquitously expressed in cell lines. {ECO:0000269|PubMed:14607844}. |
TRP14 CRISPR/Cas9 KO Plasmid (h) - sc-408490 from Santa Cruz Biotechnology
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TRP14 HDR Plasmid (h) - sc-408490-HDR from Santa Cruz Biotechnology
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TRP14 Double Nickase Plasmid (h) - sc-408490-NIC from Santa Cruz Biotechnology
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TRP14 Double Nickase Plasmid (h2) - sc-408490-NIC-2 from Santa Cruz Biotechnology
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TRP14 CRISPR Activation Plasmid (h) - sc-408490-ACT from Santa Cruz Biotechnology
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TRP14 CRISPR Activation Plasmid (h2) - sc-408490-ACT-2 from Santa Cruz Biotechnology
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TRP14 Lentiviral Activation Particles (h) - sc-408490-LAC from Santa Cruz Biotechnology
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TRP14 Lentiviral Activation Particles (h2) - sc-408490-LAC-2 from Santa Cruz Biotechnology
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TRP14 siRNA (h) - sc-93898 from Santa Cruz Biotechnology
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TRP14 shRNA Plasmid (h) - sc-93898-SH from Santa Cruz Biotechnology
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TRP14 shRNA (h) Lentiviral Particles - sc-93898-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU104981 from Sigma-Aldrich
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MISSION® esiRNA - EHU104531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22306 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22306 from Sigma-Aldrich
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TXNDC17 siRNA (Human) - CRJ3631 from Cohesion Biosciences
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TXNDC17 - MBS8226133 from MyBioSource
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shRNA set against Human Txndc1 (NM_032731.3) - SHH438188 from Creative biogene
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TXNDC17 shRNA Plasmid (Human) - CHJ3631 from Cohesion Biosciences
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TXNDC17 miRNA 3'UTR clone - MiUTR1H-10904 from Creative biogene
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