Gene Symbol |
AMER3
|
Entrez Gene |
205147
|
Alt Symbol |
FAM123C
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
APC membrane recruitment protein 3
|
Other Description |
family with sequence similarity 123C|protein FAM123C
|
Swissprots |
Q8N944 B7ZLH6
|
Accessions |
AAY24355 EAW51273 Q8N944 AK095696 BAC04612 AK289525 BAF82214 AK291424 BAF84113 BC025667 BC113445 AAI13446 BC113447 AAI13448 BC143806 AAI43807 DA102742 DA318919 DA401709 DA500900 DA773233 HQ258673 ADR83424 XM_011510793 XP_011509095 NM_001105193 NP_001098663 NM_001105194 NP_001098664 NM_001105195 NP_001098665 NM_152698 NP_689911
|
Function |
Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2. {ECO:0000250}.
|