Gene Symbol | AMER3 |
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Entrez Gene | 205147 |
Alt Symbol | FAM123C |
Species | Human |
Gene Type | protein-coding |
Description | APC membrane recruitment protein 3 |
Other Description | family with sequence similarity 123C|protein FAM123C |
Swissprots | Q8N944 B7ZLH6 |
Accessions | AAY24355 EAW51273 Q8N944 AK095696 BAC04612 AK289525 BAF82214 AK291424 BAF84113 BC025667 BC113445 AAI13446 BC113447 AAI13448 BC143806 AAI43807 DA102742 DA318919 DA401709 DA500900 DA773233 HQ258673 ADR83424 XM_011510793 XP_011509095 NM_001105193 NP_001098663 NM_001105194 NP_001098664 NM_001105195 NP_001098665 NM_152698 NP_689911 |
Function | Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2. {ECO:0000250}. |
FAM123C CRISPR/Cas9 KO Plasmid (h) - sc-415044 from Santa Cruz Biotechnology
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FAM123C HDR Plasmid (h) - sc-415044-HDR from Santa Cruz Biotechnology
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FAM123C Double Nickase Plasmid (h) - sc-415044-NIC from Santa Cruz Biotechnology
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FAM123C Double Nickase Plasmid (h2) - sc-415044-NIC-2 from Santa Cruz Biotechnology
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FAM123C CRISPR Activation Plasmid (h) - sc-415044-ACT from Santa Cruz Biotechnology
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FAM123C CRISPR Activation Plasmid (h2) - sc-415044-ACT-2 from Santa Cruz Biotechnology
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FAM123C Lentiviral Activation Particles (h) - sc-415044-LAC from Santa Cruz Biotechnology
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FAM123C Lentiviral Activation Particles (h2) - sc-415044-LAC-2 from Santa Cruz Biotechnology
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FAM123C siRNA (h) - sc-94697 from Santa Cruz Biotechnology
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FAM123C shRNA Plasmid (h) - sc-94697-SH from Santa Cruz Biotechnology
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FAM123C shRNA (h) Lentiviral Particles - sc-94697-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU138561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8151 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03245 from Sigma-Aldrich
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AMER3 siRNA (Human) - CRJ6357 from Cohesion Biosciences
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AMER3 - MBS8214979 from MyBioSource
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shRNA set against Human FAM123C (NM_152698.2) - SHH289389 from Creative biogene
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AMER3 shRNA Plasmid (Human) - CHJ6357 from Cohesion Biosciences
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FAM123C miRNA 3'UTR clone - MiUTR1H-03743 from Creative biogene
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