| Gene Symbol |
STK17B
|
| Entrez Gene |
9262
|
| Alt Symbol |
DRAK2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serine/threonine kinase 17b
|
| Other Description |
DAP kinase-related apoptosis-inducing protein kinase 2|death-associated protein kinase-related 2|serine/threonine-protein kinase 17B
|
| Swissprots |
O94768
|
| Accessions |
AAY14982 CAZ39539 CBX51402 EAW70122 O94768 AB011421 BAA34127 AK312865 BAG35717 BC016040 AAH16040 BC052561 BM994696 CR542210 CAG47006 CR542225 CAG47021 DQ892256 ABM83182 DQ895458 ABM86384 XM_011512168 XP_011510470 XM_011512169 XP_011510471 XM_011512170 XP_011510472 XM_011512171 XP_011510473 XM_011512172 XP_011510474 NM_004226 NP_004217
|
| Function |
Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis. {ECO:0000250, ECO:0000269|PubMed:9786912}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:9786912}. Cell membrane {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250}. Note=Colocalizes with STK17B at the plasma membrane. {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney. {ECO:0000269|PubMed:9786912}.
|