Gene Symbol | STK17B |
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Entrez Gene | 9262 |
Alt Symbol | DRAK2 |
Species | Human |
Gene Type | protein-coding |
Description | serine/threonine kinase 17b |
Other Description | DAP kinase-related apoptosis-inducing protein kinase 2|death-associated protein kinase-related 2|serine/threonine-protein kinase 17B |
Swissprots | O94768 |
Accessions | AAY14982 CAZ39539 CBX51402 EAW70122 O94768 AB011421 BAA34127 AK312865 BAG35717 BC016040 AAH16040 BC052561 BM994696 CR542210 CAG47006 CR542225 CAG47021 DQ892256 ABM83182 DQ895458 ABM86384 XM_011512168 XP_011510470 XM_011512169 XP_011510471 XM_011512170 XP_011510472 XM_011512171 XP_011510473 XM_011512172 XP_011510474 NM_004226 NP_004217 |
Function | Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis. {ECO:0000250, ECO:0000269|PubMed:9786912}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9786912}. Cell membrane {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250}. Note=Colocalizes with STK17B at the plasma membrane. {ECO:0000250}. |
Tissue Specificity | Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney. {ECO:0000269|PubMed:9786912}. |
DRAK2 CRISPR/Cas9 KO Plasmid (h) - sc-404787 from Santa Cruz Biotechnology
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DRAK2 HDR Plasmid (h) - sc-404787-HDR from Santa Cruz Biotechnology
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DRAK2 Double Nickase Plasmid (h) - sc-404787-NIC from Santa Cruz Biotechnology
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DRAK2 Double Nickase Plasmid (h2) - sc-404787-NIC-2 from Santa Cruz Biotechnology
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DRAK2 CRISPR Activation Plasmid (h) - sc-404787-ACT from Santa Cruz Biotechnology
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DRAK2 CRISPR Activation Plasmid (h2) - sc-404787-ACT-2 from Santa Cruz Biotechnology
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DRAK2 Lentiviral Activation Particles (h) - sc-404787-LAC from Santa Cruz Biotechnology
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DRAK2 Lentiviral Activation Particles (h2) - sc-404787-LAC-2 from Santa Cruz Biotechnology
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DRAK2 siRNA (h) - sc-38981 from Santa Cruz Biotechnology
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DRAK2 shRNA Plasmid (h) - sc-38981-SH from Santa Cruz Biotechnology
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DRAK2 shRNA (h) Lentiviral Particles - sc-38981-V from Santa Cruz Biotechnology
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DRAK2 RNAi - H00009262-R02 from Novus Biologicals
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MISSION® esiRNA - EHU021291 from Sigma-Aldrich
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MISSION® siRNA - SIHK2149 from Sigma-Aldrich
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MISSION® siRNA - SIHK2147 from Sigma-Aldrich
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MISSION® siRNA - SIHK2148 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20732 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20732 from Sigma-Aldrich
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STK17B siRNA (Human) - CRH6133 from Cohesion Biosciences
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STK17B - MBS8221002 from MyBioSource
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shRNA set against Human STK17B (NM_004226.3) - SHH419728 from Creative biogene
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STK17B shRNA Plasmid (Human) - CHH6133 from Cohesion Biosciences
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