| Gene Symbol |
KDF1
|
| Entrez Gene |
126695
|
| Alt Symbol |
C1orf172
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratinocyte differentiation factor 1
|
| Other Description |
RP11-344H11.3
|
| Swissprots |
Q5QP32 Q8N0S7 Q8NAX2
|
| Accessions |
EAX07779 Q8NAX2 AI216202 AK091952 BAC03775 BC033143 AAH33143 CR749558 CAH18355 DA041083 XM_005245735 XP_005245792 XM_011540622 XP_011538924 NM_152365 NP_689578
|
| Function |
Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Cell junction {ECO:0000250}. Note=Localized at cell borders in single layered keratinocytes. Localized at cell borders in the basal and spinous layers but is more diffusely localized in the granular layer. Colocalized with actin near the cell membrane, especially in cellular protrusions (By similarity). {ECO:0000250}.
|
![Western Blot: C1orf172 Overexpression Lysate (Adult Normal) [NBP2-05395] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C1orf172.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10470_C1orf172%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05395-img0001.jpg)