Gene Symbol | KDF1 |
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Entrez Gene | 126695 |
Alt Symbol | C1orf172 |
Species | Human |
Gene Type | protein-coding |
Description | keratinocyte differentiation factor 1 |
Other Description | RP11-344H11.3 |
Swissprots | Q5QP32 Q8N0S7 Q8NAX2 |
Accessions | EAX07779 Q8NAX2 AI216202 AK091952 BAC03775 BC033143 AAH33143 CR749558 CAH18355 DA041083 XM_005245735 XP_005245792 XM_011540622 XP_011538924 NM_152365 NP_689578 |
Function | Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell junction {ECO:0000250}. Note=Localized at cell borders in single layered keratinocytes. Localized at cell borders in the basal and spinous layers but is more diffusely localized in the granular layer. Colocalized with actin near the cell membrane, especially in cellular protrusions (By similarity). {ECO:0000250}. |
C1orf172 CRISPR/Cas9 KO Plasmid (h) - sc-414283 from Santa Cruz Biotechnology
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C1orf172 HDR Plasmid (h) - sc-414283-HDR from Santa Cruz Biotechnology
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C1orf172 Double Nickase Plasmid (h) - sc-414283-NIC from Santa Cruz Biotechnology
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C1orf172 Double Nickase Plasmid (h2) - sc-414283-NIC-2 from Santa Cruz Biotechnology
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C1orf172 CRISPR Activation Plasmid (h) - sc-414283-ACT from Santa Cruz Biotechnology
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C1orf172 CRISPR Activation Plasmid (h2) - sc-414283-ACT-2 from Santa Cruz Biotechnology
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C1orf172 Lentiviral Activation Particles (h) - sc-414283-LAC from Santa Cruz Biotechnology
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C1orf172 Lentiviral Activation Particles (h2) - sc-414283-LAC-2 from Santa Cruz Biotechnology
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C1orf172 siRNA (h) - sc-88292 from Santa Cruz Biotechnology
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C1orf172 shRNA Plasmid (h) - sc-88292-SH from Santa Cruz Biotechnology
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C1orf172 shRNA (h) Lentiviral Particles - sc-88292-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU048231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4612 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4612 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04180 from Sigma-Aldrich
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C1orf172 siRNA (Human) - CRJ4880 from Cohesion Biosciences
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C1orf172 - MBS8201640 from MyBioSource
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shRNA set against Human C1orf172 (NM_152365.2) - SHH250446 from Creative biogene
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Human C1orf172 siRNA - orb275381 from Biorbyt
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C1orf172 shRNA Plasmid (Human) - CHJ4880 from Cohesion Biosciences
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C1ORF172 miRNA 3'UTR clone - MiUTR3H-14054 from Creative biogene
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