SLC47A1

Gene Symbol SLC47A1
Entrez Gene 55244
Alt Symbol MATE1
Species Human
Gene Type protein-coding
Description solute carrier family 47 (multidrug and toxin extrusion), member 1
Other Description MATE-1|hMATE-1|multidrug and toxin extrusion 1|multidrug and toxin extrusion protein 1|solute carrier family 47, member 1
Swissprots Q86VL4 Q53HF5 Q6PD77 Q9NVA3 Q96FL8
Accessions EAW50893 EAW50894 EAW50895 Q96FL8 AK001709 BAA91852 AK222625 BAD96345 AK225360 AK293196 BAG56736 AK298254 BAG60519 AK301854 BAG63296 AK302620 BAG63865 AK304647 BAG65424 AK310270 BC010661 AAH10661 BC050592 AAH50592 BC058882 AAH58882 NM_018242 NP_060712
Function Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes. {ECO:0000269|PubMed:16330770, ECO:0000269|PubMed:16996621, ECO:0000269|PubMed:17495125, ECO:0000269|PubMed:17509534, ECO:0000269|PubMed:17582384}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16330770, ECO:0000269|PubMed:16641166}; Multi-pass membrane protein {ECO:0000269|PubMed:16330770, ECO:0000269|PubMed:16641166}. Note=Predominantly localized at the plasma membrane but also found in intracellular organelles.
Tissue Specificity Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes). {ECO:0000269|PubMed:16330770, ECO:0000269|PubMed:17509534}.

MATE1/SLC47A1 (D4C6Z) Rabbit mAb - 14550 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4C6Z
Western blot analysis of extracts from A549, Huh7, and SK-MEL-5 cells using MATE1/SLC47A1 (D4C6Z) Rabbit mAb.

MATE1 (E-13) - sc-133390 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
MATE1 (E-13): sc-133390. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

MATE1 (Q-13) - sc-133392 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
MATE1 (Q-13): sc-133392. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

Anti-SLC47A1 antibody - ab104016 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
IHC image of SLC47A1 staining in human liver formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab104016, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-SLC47A1 antibody - ab105049 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-SLC47A1 antibody - ab92295 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-SLC47A1 antibody (ab92295) at 0.1 µg/ml + Human Kidney lysate in RIPA buffer at 35 µg

Anti-SLC47A1 / MATE1 Antibody (aa500-530, AP) - LS-C240937 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A1 / MATE1 Antibody (aa500-530, APC) - LS-C240939 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A1 / MATE1 Antibody (aa500-530, Biotin) - LS-C240940 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A1 / MATE1 Antibody (aa500-530, FITC) - LS-C240941 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A1 / MATE1 Antibody (aa500-530, PE) - LS-C240943 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A1 / MATE1 Antibody (aa500-530, Azide-free, HRP) - LS-C248189 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A1 / MATE1 Antibody (aa528-541) - LS-C112814 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
SLC47A1 antibody (0.1 ug/ml) staining of Human Kidney lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SLC47A1 / MATE1 Antibody (aa500-530) - LS-C325172 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A1 / MATE1 Antibody (aa492-519) IHC-plus™ - LS-B10477 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-SLC47A1 / MATE1 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MATE1 Antibody - NBP1-87909 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: MATE1 Antibody [NBP1-87909] - Staining of human liver shows strong positivity in Kupffer cells.

MATE1 Antibody - NBP1-36989 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: MATE1 Antibody [NBP1-36989] - Analysis of MATE1 in Human Kidney lysate (35ug protein in RIPA buffer) using NBP1-36989 at 0.1ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

MATE1 Antibody - NBP1-70395 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A1 antibody produced in rabbit - HPA021987 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC47A1: <B>Cat. No. HPA021987</B>: Immunohistochemical staining of human liver shows strong positivity in Kupffer cells.

Anti-SLC47A1 antibody produced in goat - SAB2501218 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SLC47A1: <B>Cat. No. SAB2501218</B>: (0.1 μg/mL) staining of Human Kidney lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SLC47A1 Antibody - C-terminal region (OAAB02770) - OAAB02770 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

SLC47A1-Antibody-C-term - AP5354b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
SLC47A1 Antibody (C-term) (Cat. #AP5354b) western blot analysis in HepG2(lane 1),MDA-MB435(lane 2) cell line lysates (35ug/lane).This demonstrates the SLC47A1 antibody detected the SLC47A1 protein (arrow).

SLC47A1-Antibody-internal-region-near-C-Term - AF2914a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2914a (0.1 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SLC47A1 Antibody (OAEB02148) - OAEB02148 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

SLC47A1 Antibody - abx032493 from Abbexa

Host Rabbit
Clonality Polyclonal
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