Gene Symbol |
PPP1R3C
|
Entrez Gene |
5507
|
Alt Symbol |
PPP1R5
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
protein phosphatase 1, regulatory subunit 3C
|
Other Description |
PP1 subunit R5|PTG|Phosphatase 1, regulatory inhibitor subunit 5|protein phosphatase 1 regulatory subunit 3C|protein phosphatase 1 regulatory subunit 5|protein phosphatase 1, regulatory (inhibitor) subunit 3C|protein targeting to glycogen
|
Swissprots |
O95686 B2R7X0 Q9UQK1
|
Accessions |
AAD33215 EAW50107 Q9UQK1 AF087874 AAM10502 AI766011 AK299392 BAG61377 AK299398 BAG61382 AK313149 BAG35967 AM393091 CAL37969 BC012625 AAH12625 BP202053 BX537399 CAD97641 Y18207 CAA77082 NM_005398 NP_005389
|
Function |
Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types. {ECO:0000250|UniProtKB:Q7TMB3, ECO:0000269|PubMed:8985175}.
|
Top Pathways |
Insulin signaling pathway
|