Gene Symbol | MSL3 |
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Entrez Gene | 10943 |
Alt Symbol | MSL3L1 |
Species | Human |
Gene Type | protein-coding |
Description | male-specific lethal 3 homolog (Drosophila) |
Other Description | MSL3-like 1|male-specific lethal 3 homolog|male-specific lethal-3 protein-like 1 |
Swissprots | A8K165 A6NHW8 A6NCU2 B4DUV8 Q8N5Y2 B7Z227 Q9Y5Z8 Q9UG70 |
Accessions | EAW98799 EAW98800 EAW98801 EAW98802 Q8N5Y2 AF117065 AAD38499 AK000793 AK025642 AK289780 BAF82469 AK294255 BAH11713 AK300814 BAG62470 AK304419 BAG65249 AL050178 CAB43308 AL713667 CAD28473 BC010925 BC017267 BC031210 AAH31210 BI091178 BI560203 CT002798 DA172776 DA788603 DA961602 DB240082 DC395802 DQ891661 ABM82587 DQ894848 ABM85774 XM_005274440 XP_005274497 XM_006724461 XP_006724524 XM_011545442 XP_011543744 XM_011545443 XP_011543745 XM_011545444 XP_011543746 NM_001193270 NP_001180199 NM_001282174 NP_001269103 NM_006800 NP_006791 NM_078628 NP_523352 NM_078629 NP_523353 NM_078630 |
Function | May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex. {ECO:0000269|PubMed:16227571, ECO:0000269|PubMed:20018852, ECO:0000269|PubMed:20657587, ECO:0000269|PubMed:20943666, ECO:0000269|PubMed:21217699, ECO:0000269|PubMed:22547026}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart. |
MSL3L1 (N-16) - sc-131609 from Santa Cruz Biotechnology
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MSL3L1 (K-12) - sc-131608 from Santa Cruz Biotechnology
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MSL3L1 (G-19) - sc-102028 from Santa Cruz Biotechnology
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Anti-MSL3L1 antibody - ab89943 from Abcam
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Anti-MSL3L1 antibody - N-terminal - ab173484 from Abcam
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Anti-MSL3L1 / MSL3 Antibody (aa28-55, AP) - LS-C223346 from LifeSpan Bioscience
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Anti-MSL3L1 / MSL3 Antibody (aa28-55, Azide-free, HRP) - LS-C223349 from LifeSpan Bioscience
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Anti-MSL3L1 / MSL3 Antibody (aa28-55, Biotin) - LS-C223347 from LifeSpan Bioscience
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Anti-MSL3L1 / MSL3 Antibody (aa28-55, FITC) - LS-C223350 from LifeSpan Bioscience
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Anti-MSL3L1 / MSL3 Antibody (aa28-55, PE) - LS-C223351 from LifeSpan Bioscience
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Anti-MSL3L1 / MSL3 Antibody (C-Terminus) - LS-C30855 from LifeSpan Bioscience
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Anti-MSL3L1 / MSL3 Antibody (aa27-55) - LS-C323135 from LifeSpan Bioscience
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Anti-MSL3L1 / MSL3 Antibody (N-Terminus) - LS-C101795 from LifeSpan Bioscience
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Anti-MSL3L1 / MSL3 Antibody (aa287-336) - LS-C109718 from LifeSpan Bioscience
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Anti-MSL3L1 / MSL3 Antibody (aa28-55, APC) - LS-C223345 from LifeSpan Bioscience
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Anti-MSL3L1 / MSL3 Antibody (aa28-55) - LS-C158320 from LifeSpan Bioscience
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MSL3L1 Antibody - NBP1-87881 from Novus Biologicals
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MSL3L1 Antibody - NBP2-19419 from Novus Biologicals
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MSL3L1 Antibody - H00010943-B01 from Novus Biologicals
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MSL3L1 Antibody - H00010943-B01P from Novus Biologicals
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MSL3L1 Antibody - NBP1-87882 from Novus Biologicals
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Anti-MSL3L1 antibody produced in rabbit - SAB2101513 from Sigma-Aldrich
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Anti-MSL3L1 antibody produced in mouse - SAB1407078 from Sigma-Aldrich
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Anti-MSL3 antibody produced in rabbit - HPA034536 from Sigma-Aldrich
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Anti-MSL3L1 antibody produced in rabbit - SAB2104024 from Sigma-Aldrich
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