| Gene Symbol |
MRGPRX3
|
| Entrez Gene |
117195
|
| Alt Symbol |
GPCR, MRGX3, SNSR1, SNSR2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MAS-related GPR, member X3
|
| Other Description |
G protein-coupled receptor MRGX3|G protein-coupled receptor SNSR1|G protein-coupled receptor SNSR2|mas-related G-protein coupled receptor member X3|mas-related GPCR member X3|sensory neuron-specific G-protein coupled receptor 1/2
|
| Swissprots |
Q96LB0 Q8TDE0 B0M0L1 Q8TDE1
|
| Accessions |
AAK91806 AAL86878 AAL86879 EAW68417 Q96LB0 BC067292 AAH67292 EU432126 ABY87925 XM_011519882 XP_011518184 XM_011519883 XP_011518185 NM_054031 NP_473372
|
| Function |
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. {ECO:0000269|PubMed:11850634}.
|