Gene Symbol | MRGPRX3 |
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Entrez Gene | 117195 |
Alt Symbol | GPCR, MRGX3, SNSR1, SNSR2 |
Species | Human |
Gene Type | protein-coding |
Description | MAS-related GPR, member X3 |
Other Description | G protein-coupled receptor MRGX3|G protein-coupled receptor SNSR1|G protein-coupled receptor SNSR2|mas-related G-protein coupled receptor member X3|mas-related GPCR member X3|sensory neuron-specific G-protein coupled receptor 1/2 |
Swissprots | Q96LB0 Q8TDE0 B0M0L1 Q8TDE1 |
Accessions | AAK91806 AAL86878 AAL86879 EAW68417 Q96LB0 BC067292 AAH67292 EU432126 ABY87925 XM_011519882 XP_011518184 XM_011519883 XP_011518185 NM_054031 NP_473372 |
Function | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. {ECO:0000269|PubMed:11850634}. |
MRGX3 CRISPR/Cas9 KO Plasmid (h) - sc-414108 from Santa Cruz Biotechnology
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MRGX3 HDR Plasmid (h) - sc-414108-HDR from Santa Cruz Biotechnology
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MRGX3 Double Nickase Plasmid (h) - sc-414108-NIC from Santa Cruz Biotechnology
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MRGX3 Double Nickase Plasmid (h2) - sc-414108-NIC-2 from Santa Cruz Biotechnology
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MRGX3 CRISPR Activation Plasmid (h) - sc-414108-ACT from Santa Cruz Biotechnology
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MRGX3 CRISPR Activation Plasmid (h2) - sc-414108-ACT-2 from Santa Cruz Biotechnology
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MRGX3 Lentiviral Activation Particles (h) - sc-414108-LAC from Santa Cruz Biotechnology
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MRGX3 Lentiviral Activation Particles (h2) - sc-414108-LAC-2 from Santa Cruz Biotechnology
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MRGX3 siRNA (h) - sc-106240 from Santa Cruz Biotechnology
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MRGX3 shRNA Plasmid (h) - sc-106240-SH from Santa Cruz Biotechnology
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MRGX3 shRNA (h) Lentiviral Particles - sc-106240-V from Santa Cruz Biotechnology
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MRGX3 RNAi - H00117195-R02 from Novus Biologicals
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MISSION® esiRNA - EHU105531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14538 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14538 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03342 from Sigma-Aldrich
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MRGPRX3 siRNA (Human) - CRJ4560 from Cohesion Biosciences
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shRNA set against Human MRGPRX3 (NM_054031.3) - SHH344436 from Creative biogene
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Human MRGPRX3 siRNA - orb275061 from Biorbyt
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MRGPRX3 shRNA Plasmid (Human) - CHJ4560 from Cohesion Biosciences
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MRGPRX3 miRNA 3'UTR clone - MiUTR4H-TG05623 from Creative biogene
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