| Gene Symbol |
chp1
|
| Entrez Gene |
2542239
|
| Alt Symbol |
-
|
| Species |
S. pombe
|
| Gene Type |
protein-coding
|
| Description |
chromodomain protein Chp1
|
| Other Description |
-
|
| Swissprots |
Q10103
|
| Accessions |
CAA92382 Q10103 NM_001019098 NP_593666
|
| Function |
Component of the kinetochore which plays a role in stabilizing microtubules and so allowing accurate chromosome segregation. Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation. A member of the RNA-induced transcriptional silencing (RITS) complex which is involved in the biosynthesis of dsRNA from primer siRNAs provided by the RNA- directed RNA polymerase (RDRC) complex. {ECO:0000269|PubMed:10835380, ECO:0000269|PubMed:14704433, ECO:0000269|PubMed:15607976, ECO:0000269|PubMed:9722643}.
|
| Subcellular Location |
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Associates with telomeric and mating-type region heterochromatin.
|
