Gene Symbol | chp1 |
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Entrez Gene | 2542239 |
Alt Symbol | - |
Species | S. pombe |
Gene Type | protein-coding |
Description | chromodomain protein Chp1 |
Other Description | - |
Swissprots | Q10103 |
Accessions | CAA92382 Q10103 NM_001019098 NP_593666 |
Function | Component of the kinetochore which plays a role in stabilizing microtubules and so allowing accurate chromosome segregation. Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation. A member of the RNA-induced transcriptional silencing (RITS) complex which is involved in the biosynthesis of dsRNA from primer siRNAs provided by the RNA- directed RNA polymerase (RDRC) complex. {ECO:0000269|PubMed:10835380, ECO:0000269|PubMed:14704433, ECO:0000269|PubMed:15607976, ECO:0000269|PubMed:9722643}. |
Subcellular Location | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Associates with telomeric and mating-type region heterochromatin. |
Recombinant Schizosaccharomyces pombe Chromo domain-containing protein 1(chp1) - CSB-YP604554SXV CSB-EP604554SXV CSB-BP604554SXV CSB-MP604554SXV from Cusabio
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Chromo domain-containing protein 1 (chp1), partial, Recombinant Protein - MBS1411896 from MyBioSource
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