WRAP53

Gene Symbol WRAP53
Entrez Gene 55135
Alt Symbol DKCB3, TCAB1, WDR79
Species Human
Gene Type protein-coding
Description WD repeat containing, antisense to TP53
Other Description WD repeat-containing protein 79|WD repeat-containing protein WRAP53|WD40 protein Wrap53|WD40 repeat-containing protein antisense to TP53|WD40 repeat-containing protein encoding RNA antisense to p53|telomerase Cajal body protein 1
Swissprots B3KPR9 Q9NW09 Q9BUR4 Q08ET9 D3DTQ4
Accessions ACM07585 ACM07586 ACM07587 ACM07588 ACM07589 ACM07590 ACM07591 ACM07592 ACM07593 ACM07594 ACM07595 ACM07596 ACM07597 ACM07598 ACM07599 ACM07600 ACM07601 ACM07602 ACM07603 ACM07604 ACM07605 ACM07606 ACM07607 ACM07608 ACM07609 ACM07610 ACM07611 ACM07612 ACM07613 ACM07614 ACM07615 ACM07616 ACM07617 ACM07618 ACM07619 ACM07620 ACM07621 ACM07622 ACM07623 ACM07624 ACM07625 ACM07626 ACM07627 ACM07628 ACM07629 ACM07630 ACM07631 ACM07632 ACM07633 ACM07634 ACM07635 ACM07636 ACM07637 ACM07638 ACM07639 ACM07640 ACM07641 ACM07642 ACM07643 ACM07644 ACM07645 ACM07646 ACM07647 ACM07648 ACM07649 ACM07650 ACM07651 ACM07652 ACM07653 ACM07654 ACM07655 ACM07656 ACM07657 ACM07658 ACM07659 ACM07660 ACM07661 ACM07662 ACM07663 ACM07664 ACM07665 ACM07666 ACM07667 ACM07668 ACM07669 ACM07670 ACM07671 ACM07672 ACM07673 ACM07674 ACM07675 ACM07676 ACM07677 ACM07678 ACM07679 ACM07680 ACM07681 ACM07682 ACM07683 ACM07684 ACM07685 ACM07686 ACM07687 ACM07688 ACM07689 ACM07690 ACM07691 ACM07692 ACM07693 ACM07694 ACM07695 ACM07696 ACM07697 ACM07698 ACM07699 ACM07700 EAW90136 EAW90137 EAW90138 EAW90139 Q9BUR4 AK001247 BAA91579 AK056669 BAG51781 AK092370 AK225273 AK225411 AK303246 BAG64330 AY766322 AAW92115 AY766323 AAW92116 BC002336 AAH02336 DQ431240 ABD92817 DQ431241 ABD92818 XM_011523952 XP_011522254 NM_001143990 NP_001137462 NM_001143991 NP_001137463 NM_001143992 NP_001137464 NM_018081 NP_060551
Function Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post- transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage. {ECO:0000269|PubMed:19179534, ECO:0000269|PubMed:19250907}.
Subcellular Location Nucleus, Cajal body. Cytoplasm.
Tissue Specificity Expressed in all tissues and cell lines examined. {ECO:0000269|PubMed:19250907}.

WDR79 (S-18) - sc-244647 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WDR79 (S-18): sc-244647. Western blot analysis of WDR79 expression in HeLa nuclear extract.

WDR79 (T-16) - sc-244648 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-WDR79 antibody - ab99376 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling WDR79 with ab99376 at 1/200 (1µg/ml). Detection: DAB.

Anti-WDR79 antibody - ab77333 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-WDR79 antibody (ab77333) at 5 µg/ml + A431 cell lysate at 25 µgSecondaryGoat anti-mouse IgG (H&L) HRP-conjugated at 1/2500 dilution

Anti-WDR79 antibody - ab99260 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab99260 at 1/250 dilution staining WDR79 in formalin-fixed, parrafin-embedded section of Human skin carcinoma by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection utilised DAB.

Anti-WDR79 antibody - ab67994 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-WDR79 antibody (ab67994) at 1/500 dilutionLane 1 : WDR79 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-TCAB1 / WDR79 Antibody (aa1-50) - LS-C286747 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human WDR79 Immunohistochemistry. Sample: FFPE section of human skin carcinoma. Antibody: Affinity purified rabbit anti-WDR79 used at a dilution of 1:250.

Anti-TCAB1 / WDR79 Antibody (aa1-50) - LS-C288235 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human WDR79 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-WDR79 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

WDR79 Antibody - NB100-68252 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: WDR79 Antibody [NB100-68252] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. NB100-68252 used for WB at 0.04 mcg/ml (A) and 0.1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.

WDR79 Antibody - NBP1-92592 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: WDR79 Antibody [NBP1-92592] - Staining of human cell line A-431 shows localization to nuclear bodies.

WDR79 Antibody - H00055135-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: WDR79 Antibody [H00055135-D01P] - Analysis of WDR79 expression in HepG2.

WDR79 Antibody - NBP1-92593 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: WDR79 Antibody [NBP1-92593] - Staining of human colon shows strong nuclear positivity in glandular cells.

WDR79 Antibody (1F12) - H00055135-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F12
Western Blot: WDR79 Antibody (1F12) [H00055135-M04] - Analysis of WDR79 expression in A-431 (Cat # L015V1).

WDR79 Antibody - H00055135-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: WDR79 Antibody [H00055135-B01P] - Analysis of WDR79 expression in transfected 293T cell line by WDR79 polyclonal antibody. Lane 1: WDR79 transfected lysate(60.28 KDa). Lane 2: Non-transfected lysate.

Anti-WDR79 (26-40) antibody produced in rabbit - SAB1105483 from Sigma-Aldrich

Prices $279.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of U87 cells was separated on SDS-PAGE, blotted with Anti-WDR79 (26-40) (<B>Cat. No. SAB1105483</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000<BR/>2. Antibody dilution 1:1,000 + WDR79 immunizing peptide (human, 26-40)

Monoclonal Anti-WDR79 antibody produced in mouse - SAB1400602 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F12
<B>Immunoblotting</B><BR/>Monoclonal Anti-WDR79, antibody produced in mouse, clone 1F12, purified immunoglobulin: <B>Cat. No. SAB1400602</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~59.309 kDa using A-431 lysate.

Anti-WRAP53 antibody produced in rabbit - HPA028130 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-WRAP53: <B>Cat. No. HPA028130</B>: Immunohistochemical staining of human colon shows strong nuclear positivity in glandular cells.

Anti-WRAP53 antibody produced in rabbit - HPA023026 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-WRAP53: <B>Cat. No. HPA023026</B>: Immunohistochemical staining of human duodenum shows nuclear and nucleolar positivity in glandular cells.

Anti-WDR79 antibody produced in rabbit - SAB1411031 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-WDR79: <B>Cat. No. SAB1411031</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~59.3 kDa using HepG2 lysate.

Anti-WDR79 antibody produced in mouse - SAB1407616 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-WDR79: <B>Cat. No. SAB1407616</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~60.3 kDa using WDR79 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-WDR79 (526-540) antibody produced in rabbit - SAB1105484 from Sigma-Aldrich

Prices $279.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

WDR79-Antibody-monoclonal-M04 - AT4537a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F12
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .

WDR79 antibody - orb155411 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

WRAP53 antibody - 70R-21328 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

WDR79 Antibody - abx036111 from Abbexa

Host Rabbit
Clonality Polyclonal
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