WRAP53

Gene Symbol	WRAP53
Entrez Gene	55135
Alt Symbol	DKCB3, TCAB1, WDR79
Species	Human
Gene Type	protein-coding
Description	WD repeat containing, antisense to TP53
Other Description	WD repeat-containing protein 79|WD repeat-containing protein WRAP53|WD40 protein Wrap53|WD40 repeat-containing protein antisense to TP53|WD40 repeat-containing protein encoding RNA antisense to p53|telomerase Cajal body protein 1
Swissprots	B3KPR9 Q9NW09 Q9BUR4 Q08ET9 D3DTQ4
Accessions	ACM07585 ACM07586 ACM07587 ACM07588 ACM07589 ACM07590 ACM07591 ACM07592 ACM07593 ACM07594 ACM07595 ACM07596 ACM07597 ACM07598 ACM07599 ACM07600 ACM07601 ACM07602 ACM07603 ACM07604 ACM07605 ACM07606 ACM07607 ACM07608 ACM07609 ACM07610 ACM07611 ACM07612 ACM07613 ACM07614 ACM07615 ACM07616 ACM07617 ACM07618 ACM07619 ACM07620 ACM07621 ACM07622 ACM07623 ACM07624 ACM07625 ACM07626 ACM07627 ACM07628 ACM07629 ACM07630 ACM07631 ACM07632 ACM07633 ACM07634 ACM07635 ACM07636 ACM07637 ACM07638 ACM07639 ACM07640 ACM07641 ACM07642 ACM07643 ACM07644 ACM07645 ACM07646 ACM07647 ACM07648 ACM07649 ACM07650 ACM07651 ACM07652 ACM07653 ACM07654 ACM07655 ACM07656 ACM07657 ACM07658 ACM07659 ACM07660 ACM07661 ACM07662 ACM07663 ACM07664 ACM07665 ACM07666 ACM07667 ACM07668 ACM07669 ACM07670 ACM07671 ACM07672 ACM07673 ACM07674 ACM07675 ACM07676 ACM07677 ACM07678 ACM07679 ACM07680 ACM07681 ACM07682 ACM07683 ACM07684 ACM07685 ACM07686 ACM07687 ACM07688 ACM07689 ACM07690 ACM07691 ACM07692 ACM07693 ACM07694 ACM07695 ACM07696 ACM07697 ACM07698 ACM07699 ACM07700 EAW90136 EAW90137 EAW90138 EAW90139 Q9BUR4 AK001247 BAA91579 AK056669 BAG51781 AK092370 AK225273 AK225411 AK303246 BAG64330 AY766322 AAW92115 AY766323 AAW92116 BC002336 AAH02336 DQ431240 ABD92817 DQ431241 ABD92818 XM_011523952 XP_011522254 NM_001143990 NP_001137462 NM_001143991 NP_001137463 NM_001143992 NP_001137464 NM_018081 NP_060551
Function	Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post- transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage. {ECO:0000269|PubMed:19179534, ECO:0000269|PubMed:19250907}.
Subcellular Location	Nucleus, Cajal body. Cytoplasm.
Tissue Specificity	Expressed in all tissues and cell lines examined. {ECO:0000269|PubMed:19250907}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

WDR79 293T Cell Transient Overexpression Lysate(Denatured) - H00055135-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

WRAP53 overexpression lysate - LY413323 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

WRAP53 overexpression lysate - LY428450 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

WRAP53 overexpression lysate - LY428451 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

WRAP53 overexpression lysate - LY428452 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

WRAP53 293 Cell Lysate - 406460 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

WDR79 Overexpression Lysate (Native) - NBL1-17832 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

WRAP53 Over-expression Lysate Product - GWB-F1AFBD from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

WDR79 Overexpression Lysate (Native) - NBP2-11363 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

WDR79 Overexpression Lysate (Native) - NBP2-11362 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

WDR79 Overexpression Lysate (Native) - NBP2-11361 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

WDR79 Overexpression Lysate (Denatured) - H00055135-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

WDR79 Overexpression Lysate (Denatured) - H00055135-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human WRAP53 Knockdown Stable Cell Line - CSC-DC017530 from Creative biogene Category Cell Line Species Human

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