cig2

Gene Symbol cig2
Entrez Gene 2543481
Alt Symbol cyc17
Species S. pombe
Gene Type protein-coding
Description G1/S-specific B-type cyclin Cig2
Other Description -
Swissprots P36630
Accessions CAC21469 P36630 NM_001019319 NP_593889
Function Essential for the control of the cell cycle at the G2/M and G1/S (mitosis) transition. Interacts with the cdc2 protein kinase to form MPF. Interaction with res2 promotes the phosphorylation of res1 and inhibits MBF-dependent gene transcription. Forms an autoregulating feedback-inhibition loop with MBF which is important for normal regulation of the cell cycle. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis. Negatively regulates conjugation via interacting with cell cycle 'start' genes. Degraded by skp1, pop1 and pop2 in the G2 and M phases of the cell cycle. {ECO:0000269|PubMed:11163211, ECO:0000269|PubMed:11781565, ECO:0000269|PubMed:14970237, ECO:0000269|PubMed:7909513, ECO:0000269|PubMed:8264644, ECO:0000269|PubMed:8455610, ECO:0000269|PubMed:8657126}.
Subcellular Location Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Top Pathways Cell cycle - yeast

Cig2 (CIG2 3A11/5) - sc-53223 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Cig2 antibody [CIG 3A11/5] - ab10881 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone CIG 3A11/5
All lanes : Anti-Cig2 antibody [CIG 3A11/5] (ab10881) at 1/1000 dilutionLane 1 : 20ug untreated S. pombe wildtype cells, whole cell lysateLane 2 : 20ug S. pombe wildtype cells 8mM HU treated for 1 hour, whole cell lysateLane 3 : 20ug S. pombe wildtype cells 8mM HU treated for 2 hours, whole cell lysateLane 4 : 20ug S. pombe wildtype cells 8mM HU treated for 3 hours, whole cell lysateSecondaryHRP conjugated sheep anti-mouse antibodydeveloped using the ECL techniqueObserved band size : 50 kDa (why is the actual band size different from the predicted?)Exposure time :  1 minuteThis image is courtesy of an anonymous AbreviewSee Abreview

Cig2 Antibody - GWB-CCCC25 from Genway Biotech

Prices $431.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CIG2 3A11/5

Anti-Schizosaccharomyces pombe Cig2 Monoclonal antibody, Clone EKI 5C23/7 - DMABT-Z59434 from Creative Diagnostics

Host Mouse
Clonality Monoclonal
Clone EKI 5C23/7
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