| Gene Symbol | cig2 |
|---|---|
| Entrez Gene | 2543481 |
| Alt Symbol | cyc17 |
| Species | S. pombe |
| Gene Type | protein-coding |
| Description | G1/S-specific B-type cyclin Cig2 |
| Other Description | - |
| Swissprots | P36630 |
| Accessions | CAC21469 P36630 NM_001019319 NP_593889 |
| Function | Essential for the control of the cell cycle at the G2/M and G1/S (mitosis) transition. Interacts with the cdc2 protein kinase to form MPF. Interaction with res2 promotes the phosphorylation of res1 and inhibits MBF-dependent gene transcription. Forms an autoregulating feedback-inhibition loop with MBF which is important for normal regulation of the cell cycle. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis. Negatively regulates conjugation via interacting with cell cycle 'start' genes. Degraded by skp1, pop1 and pop2 in the G2 and M phases of the cell cycle. {ECO:0000269|PubMed:11163211, ECO:0000269|PubMed:11781565, ECO:0000269|PubMed:14970237, ECO:0000269|PubMed:7909513, ECO:0000269|PubMed:8264644, ECO:0000269|PubMed:8455610, ECO:0000269|PubMed:8657126}. |
| Subcellular Location | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. |
| Top Pathways | Cell cycle - yeast |
Recombinant Schizosaccharomyces pombe G2/mitotic-specific cyclin cig2(cig2) - CSB-YP339711SXV CSB-EP339711SXV CSB-BP339711SXV CSB-MP339711SXV from Cusabio
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G2/mitotic-specific cyclin cig2 (cig2), Recombinant Protein - MBS1015034 from MyBioSource
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