CD4

Gene Symbol CD4
Entrez Gene 920
Alt Symbol CD4mut
Species Human
Gene Type protein-coding
Description CD4 molecule
Other Description CD4 antigen (p55)|CD4 receptor|T-cell surface antigen T4/Leu-3|T-cell surface glycoprotein CD4
Swissprots P01730 Q9UDE5 Q5U066 D3DUS5 B2R737 Q4ZGK2
Accessions AAA16069 AAB51309 AAY22175 CAA60883 EAW88738 EAW88739 P01730 AK300052 BAG61861 AK303968 BAG64892 AK308344 AK310652 AK310677 AK310687 AK310750 AK311495 AK312828 BAG35684 AK315898 BAF98789 AK316461 BAH14832 AK316462 BAH14833 BC025782 AAH25782 BT019791 AAV38594 BT019811 AAV38614 BX378810 CA305950 DA384217 DA463597 DA619688 DA639898 DB123455 DQ892052 ABM82978 DQ895246 ABM86172 M12807 AAA35572 S79267 AAB35273 U40625 AAB02789 XM_011521039 XP_011519341 NM_000616 NP_000607 NM_001195014 NP_001181943 NM_001195015 NP_001181944 NM_001195016 NP_001181945 NM_001195017 NP_001181946 NR_036545
Function Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12517957}; Single-pass type I membrane protein {ECO:0000269|PubMed:12517957}. Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
Top Pathways Hematopoietic cell lineage, T cell receptor signaling pathway, Cell adhesion molecules (CAMs), Primary immunodeficiency, Antigen processing and presentation

CD4 (Edu-2) Mouse mAb - 3563 from Cell Signaling Technology

Prices $239.00
Sizes 400 µl (100 tests)
Host Mouse
Clonality Monoclonal
Clone Edu-2
Flow cytometric analysis of peripheral blood using CD4 (Edu-2) Mouse mAb.

CD4 (H-370) - sc-7219 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD4 (H-370): sc-7219. Western blot analysis of CD4 expression in CCRF-CEM whole cell lysate.

CD4 (MT310) - sc-19641 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD4 (MT310) Alexa Fluor 488: sc-19641 AF488. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG1: sc-3890.

CD4 (18-46) - sc-1176 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD4 (18-46) FITC: sc-1176 FITC. FCM analysis of Hut78 cells. Black line histogram represents the isotype control, normal mouse IgG<sub>2b</sub>: sc-2857.

CD4 (C-18) - sc-1140 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD4 (C-18): sc-1140. Western blot analysis of CD4 expression in mouse thymus extract.

CD4 (B486A1) - sc-32811 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD4 (B486A1) PE: sc-32811 PE. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>, sc-2866.

CD4 (EDU-2) - sc-51544 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD4 (EDU-2): sc-51544. Indirect FCM analysis of human peripheral blood leukocytes stained with CD4 (EDU-2), followed by PE-conjugated goat anti-mouse IgG<sub>2a</sub>: sc-3765. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-3878.

CD4 (RIV6) - sc-52385 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD4 (RIV6): sc-52385. Indirect FCM analysis of human peripheral blood leukocytes stained with CD4 (RIV6), followed by PE-conjugated goat anti-mouse IgG<sub>2a</sub>: sc-3765. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-3878.

CD4 (YNB46.1.8) - sc-59041 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
CD4 (YNB46.1.8): sc-59041. Western blot analysis of CD4 expression in CCRF-CEM whole cell lysate.

CD4 (5B4) - sc-70670 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD4 (5B4): sc-70670. Western blot analysis of CD4 expression in HL-60 whole cell lysate.

CD4 (6A17) - sc-70659 from Santa Cruz Biotechnology

Prices $279.00
Sizes 250 µl supernatant
Host Mouse
Clonality Monoclonal
CD4 (6A17): sc-70659. Western blot analysis of CD4 expression in SUP-T1 (A) and CCRF-CEM (B) whole cell lysates.

CD4 (3H739) - sc-70674 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

CD4 (0.N.52) - sc-70660 from Santa Cruz Biotechnology

Prices $279.00
Sizes 250 µl supernatant
Host Mouse
Clonality Monoclonal
CD4 (0.N.52): sc-70660. Western blot analysis of CD4 expression in SUP-T1 (A) and CCRF-CEM (B) whole cell lysates.

CD4 (10C12) - sc-59031 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

CD4 (BC/1F6) - sc-59034 from Santa Cruz Biotechnology

Prices $279.00
Sizes 250 µl supernatant
Host Mouse
Clonality Monoclonal
CD4 (BC/1F6): sc-59034. Western blot analysis of CD4 expression in SUP-T1 (A) and CCRF-CEM (B) whole cell lysates.

CD4 (1F6) - sc-59032 from Santa Cruz Biotechnology

Prices $279.00
Sizes 250 µl supernatant
Host Mouse
Clonality Monoclonal
CD4 (1F6): sc-59032. Western blot analysis of CD4 expression in human PBL (A), SUP-T1 (B), CCRF-CEM (C) and HL-60 (D) whole cell lysates.

CD4 (MEM-241) - sc-51547 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD4 (MEM-241): sc-51547. Indirect FCM analysis of human peripheral blood leukocytes stained with CD4 (MEM-241), followed by PE-conjugated goat anti-mouse IgG<sub>1</sub>: sc-3764. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877.

CD4 (MEM-115) - sc-51545 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD4 (MEM-115): sc-51545. Indirect FCM analysis of human peripheral blood leukocytes stained with CD4 (MEM-115), followed by PE-conjugated goat anti-mouse IgG<sub>2a</sub>: sc-3765. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-3878.

CD4 (RPA-T4) - sc-53664 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD4 (RPA-T4): sc-53664. Western blot analysis of CD4 expression in CCRF-CEM whole cell lysate.

Anti-CD4 + CD8 antibody [EDU-2 + 733] (Dual color: FITC + PE) - ab1232 from Abcam

Prices $216.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone EDU-2 + 733

Anti-CD4 (phospho S433) antibody - ab61011 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human brain tissue using ab61011 at a 1/50 dilution.

Anti-CD4 antibody - ab187745 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CD4 antibody (ab187745) at 1/500 dilution + SKNMC cell lysate

Anti-CD4 antibody - ab192449 from Abcam

Host Goat
Clonality Polyclonal
Anti-CD4 antibody (ab192449) at 1/500 dilution + Spleen lysate at 100 µgSecondaryRabbit polyclonal to goat IgG (HRP) at 1/10000 dilution

Anti-CD4 antibody - ab117306 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD4 antibody (ab117306) at 1 µg/ml (Milk blocking - 3%)Lane 1 : Thymus (Human) Tissue Lysate - adult normal tissueLane 2 : Lymph node (Human) Tissue Lysate - adult normal tissueLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CD4 antibody [10C12] - ab25804 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10C12
Search more