Gene Symbol | IGFBP2 |
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Entrez Gene | 3485 |
Alt Symbol | IBP2, IGF-BP53 |
Species | Human |
Gene Type | protein-coding |
Description | insulin-like growth factor binding protein 2, 36kDa |
Other Description | IBP-2|IGF-binding protein 2|IGFBP-2|insulin-like growth factor-binding protein 2 |
Swissprots | Q14619 P18065 Q9UCL3 |
Accessions | AAA36048 AAB22308 AAQ87876 AAY14661 AAY15079 CBX47602 EAW70573 P18065 A09809 CAA00862 AB209509 BAD92746 AL559513 BC004312 AAH04312 BC009902 AAH09902 BC012769 AAH12769 BC071967 AAH71967 DQ893450 ABM84376 EU176752 ABW03553 M35410 AAA03246 X16302 CAA34373 NM_000597 NP_000588 |
Function | Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. {ECO:0000269|PubMed:19081843}. |
Subcellular Location | Secreted. |
IGFBP2 CRISPR/Cas9 KO Plasmid (h) - sc-401076 from Santa Cruz Biotechnology
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IGFBP2 HDR Plasmid (h) - sc-401076-HDR from Santa Cruz Biotechnology
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IGFBP2 Double Nickase Plasmid (h) - sc-401076-NIC from Santa Cruz Biotechnology
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IGFBP2 Double Nickase Plasmid (h2) - sc-401076-NIC-2 from Santa Cruz Biotechnology
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IGFBP2 CRISPR Activation Plasmid (h) - sc-401076-ACT from Santa Cruz Biotechnology
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IGFBP2 CRISPR Activation Plasmid (h2) - sc-401076-ACT-2 from Santa Cruz Biotechnology
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IGFBP2 Lentiviral Activation Particles (h) - sc-401076-LAC from Santa Cruz Biotechnology
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IGFBP2 Lentiviral Activation Particles (h2) - sc-401076-LAC-2 from Santa Cruz Biotechnology
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IGFBP2 siRNA (h) - sc-37195 from Santa Cruz Biotechnology
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IGFBP2 shRNA Plasmid (h) - sc-37195-SH from Santa Cruz Biotechnology
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IGFBP2 shRNA (h) Lentiviral Particles - sc-37195-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU054511 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10521 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01998 from Sigma-Aldrich
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IGFBP2 siRNA (Human) - CRH2356 from Cohesion Biosciences
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IGFBP2 - MBS829207 from MyBioSource
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IGFBP2 HDR Plasmid (h2) - sc-401076-HDR-2 from Santa Cruz Biotechnology
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IGFBP2 CRISPR/Cas9 KO Plasmid (h2) - sc-401076-KO-2 from Santa Cruz Biotechnology
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shRNA set against Human IGFBP2 (NM_000597.2) - SHH317541 from Creative biogene
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shRNA set against Human IGFBP2(NM_000597.2) - SHL168600 from Creative biogene
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Human IGFBP2 siRNA - orb262858 from Biorbyt
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IGFBP2 shRNA Plasmid (Human) - CHH2356 from Cohesion Biosciences
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IGFBP2 miRNA 3'UTR clone - MiUTR1H-04839 from Creative biogene
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