Gene Symbol | TRPS1 |
---|---|
Entrez Gene | 7227 |
Alt Symbol | GC79, LGCR |
Species | Human |
Gene Type | protein-coding |
Description | trichorhinophalangeal syndrome I |
Other Description | tricho-rhino-phalangeal syndrome type I protein|zinc finger protein GC79|zinc finger transcription factor Trps1 |
Swissprots | Q9UHH6 B4E1Z5 Q9NWE1 Q9UHF7 Q08AU2 |
Accessions | EAW91952 Q9UHF7 AF183810 AAF23614 AF264784 AAG21134 AK000948 BAA91441 AK021470 AK021511 AK304046 BAG64957 AK309357 BC125020 AAI25021 DA399687 DC339831 XM_005251049 XP_005251106 XM_006716625 XP_006716688 XM_011517264 XP_011515566 XM_011517265 XP_011515567 XM_011517266 XP_011515568 XM_011517267 XP_011515569 XM_011517268 XP_011515570 NM_001282902 NP_001269831 NM_001282903 NP_001269832 NM_014112 NP_054831 |
Function | Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. {ECO:0000269|PubMed:12885770, ECO:0000269|PubMed:17391059}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12885770}. |
Tissue Specificity | Ubiquitously expressed in the adult. Found in fetal brain, lung, kidney, liver, spleen and thymus. More highly expressed in androgen-dependent than in androgen-independent prostate cancer cells. |
TRPS1 CRISPR/Cas9 KO Plasmid (h) - sc-403037 from Santa Cruz Biotechnology
|
||||||||
TRPS1 HDR Plasmid (h) - sc-403037-HDR from Santa Cruz Biotechnology
|
||||||||
TRPS1 Double Nickase Plasmid (h) - sc-403037-NIC from Santa Cruz Biotechnology
|
||||||||
TRPS1 Double Nickase Plasmid (h2) - sc-403037-NIC-2 from Santa Cruz Biotechnology
|
||||||||
TRPS1 CRISPR Activation Plasmid (h) - sc-403037-ACT from Santa Cruz Biotechnology
|
||||||||
TRPS1 CRISPR Activation Plasmid (h2) - sc-403037-ACT-2 from Santa Cruz Biotechnology
|
||||||||
TRPS1 Lentiviral Activation Particles (h) - sc-403037-LAC from Santa Cruz Biotechnology
|
||||||||
TRPS1 Lentiviral Activation Particles (h2) - sc-403037-LAC-2 from Santa Cruz Biotechnology
|
||||||||
TRPS1 siRNA (h) - sc-106642 from Santa Cruz Biotechnology
|
||||||||
TRPS1 shRNA Plasmid (h) - sc-106642-SH from Santa Cruz Biotechnology
|
||||||||
TRPS1 shRNA (h) Lentiviral Particles - sc-106642-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU003611 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN22061 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22061 from Sigma-Aldrich
|
||||||||
TRPS1 siRNA (Human) - CRH4951 from Cohesion Biosciences
|
||||||||
TRPS1 RNAi - H00007227-R01 from Novus Biologicals
|
||||||||
TRPS1 - MBS8226183 from MyBioSource
|
||||||||
shRNA set against Human Trps1 (NM_014112.2) - SHH435720 from Creative biogene
|
||||||||
shRNA set against Human TRPS1(NM_014112.2) - SHL097668 from Creative biogene
|
||||||||
TRPS1 shRNA Plasmid (Human) - CHH4951 from Cohesion Biosciences
|
||||||||
TRPS1 miRNA 3'UTR clone - MiUTR1H-10793 from Creative biogene
|