TRPS1

Gene Symbol	TRPS1
Entrez Gene	7227
Alt Symbol	GC79, LGCR
Species	Human
Gene Type	protein-coding
Description	trichorhinophalangeal syndrome I
Other Description	tricho-rhino-phalangeal syndrome type I protein\|zinc finger protein GC79\|zinc finger transcription factor Trps1
Swissprots	Q9UHH6 B4E1Z5 Q9NWE1 Q9UHF7 Q08AU2
Accessions	EAW91952 Q9UHF7 AF183810 AAF23614 AF264784 AAG21134 AK000948 BAA91441 AK021470 AK021511 AK304046 BAG64957 AK309357 BC125020 AAI25021 DA399687 DC339831 XM_005251049 XP_005251106 XM_006716625 XP_006716688 XM_011517264 XP_011515566 XM_011517265 XP_011515567 XM_011517266 XP_011515568 XM_011517267 XP_011515569 XM_011517268 XP_011515570 NM_001282902 NP_001269831 NM_001282903 NP_001269832 NM_014112 NP_054831
Function	Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. {ECO:0000269\|PubMed:12885770, ECO:0000269\|PubMed:17391059}.
Subcellular Location	Nucleus {ECO:0000269\|PubMed:12885770}.
Tissue Specificity	Ubiquitously expressed in the adult. Found in fetal brain, lung, kidney, liver, spleen and thymus. More highly expressed in androgen-dependent than in androgen-independent prostate cancer cells.

TRPS1 (N-18) - sc-26974 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TRPS1 (N-18): sc-26974. Western blot analysis of TRPS1 expression in rat brain tissue extract.

TRPS1 (G-20) - sc-26975 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TRPS1 (C-17) - sc-26976 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-TRPS1 antibody - ab125197 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-TRPS1 antibody (ab125197) at 0.1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : 293T whole cell lysate at 50 µgLane 4 : Jurkat whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-TRPS1 antibody - ab111439 from Abcam

Prices	$378.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

ab111439, at 1/50 dilution, staining TRPS1 in paraffin-embedded Human lung carcinoma tissue by Immunohistochemistry, in the presence (right panel) or absence (left panel) of immunising peptide.

Anti-TRPS1 antibody - ab176712 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-TRPS1 antibody (ab176712) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : 293T whole cell lysate at 50 µgLane 4 : Jurkat whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-TRPS1 antibody - ab176971 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of formalin-fixed paraffin-embedded Human lung carcinoma tissue labeling TRPS1 with ab176971 at a 1/100 dilution.

Anti-TRPS1 antibody - N-terminal - ab199930 from Abcam

Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-TRPS1 antibody - N-terminal (ab199930) at 1/1000 dilutionLane 1 : HeLa total cell extractLane 2 : Jurkat total cell extract

Anti-TRPS1 Antibody (aa1-50) - LS-C290229 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TRPS1 Antibody (aa1000-1050) - LS-C290231 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TRPS1 Antibody (aa121-170) - LS-C119308 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

IHC of paraffin-embedded human lung carcinoma tissue, using TRPS1 Antibody. The picture on the right is treated with the synthesized peptide.

TRPS1 Antibody [Unconjugated] - AF4838 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Goat
Clonality	Polyclonal

Western blot shows lysates of MDA‑MB‑453 human breast cancer cell line and MCF‑7 human breast cancer cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human TRPS1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4838) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for TRPS1 at approximately 165 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 2.

TRPS1 Antibody - NBP1-55747 from Novus Biologicals

Prices	$229.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: TRPS1 Antibody [NBP1-55747] - Analysis of paraffin-embedded human lung carcinoma tissue, using TRPS1 Antibody. The picture on the right is treated with the synthesized peptide.

TRPS1 Antibody - NBP2-04120 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

TRPS1 Antibody - NBP2-04082 from Novus Biologicals

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug) and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-TRPS1 antibody NBP2-04082 used for WB at 0.04 ug/ml (A) and 0.4 ug/ml (B) and used for IP at 6 ug/mg lysate. TRPS1 was also immunoprecipitated by rabbit anti-TRPS1 antibody NBP2-04120, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B).

Anti-TRPS1, N-Terminal antibody produced in rabbit - SAB4503035 from Sigma-Aldrich

Prices	$335.50
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-TRPS1: <B>Cat. No. SAB4503035</B>: Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Anti-TRPS1 antibody. Cells on the left were treated with the Anti-TRPS1 antibody. Cells on the right (negative control) were treated with both Anti-TRPS1 antibody and the synthesized immunogen peptide.

Anti-TRPS1 antibody produced in rabbit - SAB4300902 from Sigma-Aldrich

Prices	$230.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-TRPS1: <B>Cat. No. SAB4300902</B>: Immunohistochemical analysis of paraffin-embedded Human lung carcinoma tissue using Anti-TRPS1 antibody.

Human TRPS1 Antibody - AF4838 from R&D Systems

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Goat

Detection of Human TRPS1 by Western Blot. Western blot shows lysates of MDA-MB-453 human breast cancer cell line and MCF-7 human breast cancer cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human TRPS1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4838) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109 ). A specific band was detected for TRPS1 at approximately 165 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 2 .

Human TRPS1 Affinity Purified Polyclonal Ab, Goat IgG - AF4838-SP from R&D Systems

Host	Goat
Clonality	Polyclonal

TRPS1 Antibody (OAAF02728) - OAAF02728 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

TRPS1 antibody - 70R-21015 from Fitzgerald

Prices	$375.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

TRPS1 Antibody - abx013836 from Abbexa

Host	Rabbit
Clonality	Polyclonal

TRPS1 Antibody - abx037253 from Abbexa

Host	Rabbit
Clonality	Polyclonal

TRPS1 antibody - 20003-1-AP from Acris Antibodies

Prices	$270.00
Sizes	150 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry of paraffin-embedded human kidney slide using 20003-1-AP( TRPS1 Antibody) at dilution of 1:50

TRPS1 pSer1 antibody - 21938-1-AP from Acris Antibodies

Prices	$270.00
Sizes	150 µl
Host	Rabbit
Clonality	Polyclonal

HEK-293 cells were subjected to SDS PAGE followed by western blot with 21938-1-AP(TRPS1 antibody) at dilution of 1:1000

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