| Gene Symbol | Fbxo32 |
|---|---|
| Entrez Gene | 171043 |
| Alt Symbol | Atrogin1, MAFbx |
| Species | Rat |
| Gene Type | protein-coding |
| Description | F-box protein 32 |
| Other Description | F-box only protein 32|atrogin-1|atrophy gene 1|muscle atrophy F-box protein |
| Swissprots | Q91Z62 |
| Accessions | EDM16222 Q91Z62 AY059628 AAL16406 NM_133521 NP_598205 |
| Function | Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Shuttles between Cytoplasm and the nucleus. {ECO:0000250}. |
| Tissue Specificity | Specifically expressed in cardiac and skeletal muscle. |
CompoZr® Knockout ZFN Kit - CKOZFN53923 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND53923 from Sigma-Aldrich
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FBXO32 siRNA (Rat) - CRR3308 from Cohesion Biosciences
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FBXO32 - MBS8232574 from MyBioSource
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shRNA set against Rat FBXO32 (NM_133521.1) - SHH293225 from Creative biogene
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shRNA set against Rat Fbxo32(NM_133521.1) - SHH052463 from Creative biogene
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MAFbx siRNA (r) - sc-156172 from Santa Cruz Biotechnology
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MAFbx shRNA Plasmid (r) - sc-156172-SH from Santa Cruz Biotechnology
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FBXO32 shRNA Plasmid (Rat) - CHR3308 from Cohesion Biosciences
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FBXO32 miRNA 3'UTR clone - MiUTR1R-01848 from Creative biogene
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