FDFT1

Gene Symbol FDFT1
Entrez Gene 2222
Alt Symbol DGPT, ERG9, SQS, SS
Species Human
Gene Type protein-coding
Description farnesyl-diphosphate farnesyltransferase 1
Other Description FPP:FPP farnesyltransferase|presqualene-di-diphosphate synthase|squalene synthase|squalene synthetase
Swissprots B4DJE5 B3KQ95 B7Z1J3 Q96GT0 B4DT56 P37268
Accessions EAW65628 EAW65629 P37268 AA679352 AI679762 AK057726 BAG51957 AK098682 AK293545 BAH11529 AK296043 BAG58807 AK297868 BAG60195 AK300059 BAG61868 AK300245 BAG62012 AK301617 BAG63102 AK311246 AK311362 AK315993 BAH14364 AK316033 BAH14404 AK316182 BAH14553 AK316351 BAH14722 AK316531 BAH14902 AK316534 BAH14905 BC003573 AAH03573 BC009251 AAH09251 BC029641 AAH29641 BC034440 BE384903 BG752446 BI765996 BT006704 AAP35350 CR457033 CAG33314 DC314061 DC387127 DC387479 DC396859 DQ890697 ABM81623 DQ893882 ABM84808 L06070 AAA60582 L06105 AAA36645 S76822 AAB33404 X69141 CAA48896 XM_006716247 XP_006716310 NM_001287742 NP_001274671 NM_001287743 NP_001274672 NM_001287744 NP_001274673 NM_001287745 NP_001274674 NM_001287747 NP_001274676 NM_001287748 NP_001274677 NM_001287749 NP_001274678 NM_001287750 NP_001274679 NM_001287751 NP_001274680 NM_001287756 NP_001274685 NM_004462 NP_004453
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Top Pathways Steroid biosynthesis

Squalene synthetase (A-7) - sc-271602 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Squalene synthetase (A-7): sc-271602. Western blot analysis of Squalene synthetase expression in non-transfected: sc-117752 (A) and human Squalene synthetase transfected: sc-113914 (B) 293T whole cell lysates.

Squalene synthetase (B-8) - sc-365101 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Squalene synthetase (B-8): sc-365101. Immunofluores-cence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Squalene synthetase (C-10) - sc-271143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Squalene synthetase (C-10): sc-271143. Immunoperox-idase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing cytoplasmic staining of glandular cells.

Squalene synthetase (H-300) - sc-99145 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Squalene synthetase (H-300): sc-99145. Western blot analysis of Squalene synthetase expression in non-transfected: sc-117752 (A) and human Squalene synthetase transfected: sc-113914 (B) 293T whole cell lysates.

Squalene synthetase (Y-17) - sc-49758 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Squalene synthetase (Y-17): sc-49758. Western blot analysis of Squalene synthetase expression in rat liver (A) and mouse liver (B) tissue extracts.

Anti-FDFT1 antibody - ab71637 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-FDFT1 antibody (ab71637) at 1/100 dilution + Mouse cerebellum tissue lysate at 12.5 µg

Anti-FDFT1 antibody - ab24429 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-FDFT1 antibody (ab24429) at 1/1000 dilutionLane 1 : Total protein extract from E. coli with ~50ng to 100ng of a negative control fusion protein with an irrelevant antigen at 20 ugLane 2 : Total protein extract from E. coli with ~50ng to 500ng of the antigen fusion protein at 20 ugSecondaryRabbit anti-mouse IgG + IgM, (H+L) horseradish peroxidase conjugated at 1/5000 dilution

Anti-FDFT1 antibody - ab123271 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-FDFT1 antibody (ab123271) at 1/100 dilution + HepG2 cell lysate at 35 µg

Anti-FDFT1 antibody [1H9] - ab119267 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H9
All lanes : Anti-FDFT1 antibody [1H9] (ab119267) (1/2000)Lane 1 : HEK293T cells transfected with vector control cDNA for 48 hoursLane 2 : HEK293T cells transfected with FDFT1 cDNA for 48 hoursLysates/proteins at 5 µg per lane.

Anti-FDFT1 antibody [2F10] - ab119374 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F10
All lanes : Anti-FDFT1 antibody [2F10] (ab119374) at 1/200 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY FDFT1 cDNALysates/proteins at 5 µg per lane.

Anti-FDFT1 antibody [EPR16481] - ab195046 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16481
All lanes : Anti-FDFT1 antibody [EPR16481] (ab195046) at 1/10000 dilutionLane 1 : Human fetal brain lysateLane 2 : Human fetal spleen lysateLysates/proteins at 10 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-FDFT1 antibody [EPR4626] - ab109723 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4626
All lanes : Anti-FDFT1 antibody [EPR4626] (ab109723) at 1/1000 dilutionLane 1 : Fetal liver lysateLane 2 : HepG2 lysateLane 3 : Molt-4 lysateLane 4 : SH-SY5Y lysates Lysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilution

Anti-FDFT1 / Squalene Synthase Antibody (clone 2F10) - LS-C173269 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F10
IHC of paraffin-embedded Human endometrium tissue using anti-FDFT1 mouse monoclonal antibody.

Anti-FDFT1 / Squalene Synthase Antibody (aa101-150) - LS-C81266 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.

Anti-FDFT1 / Squalene Synthase Antibody (aa332-361, AP) - LS-C214169 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FDFT1 / Squalene Synthase Antibody (aa332-361, APC) - LS-C214170 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FDFT1 / Squalene Synthase Antibody (aa332-361, Biotin) - LS-C214171 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FDFT1 / Squalene Synthase Antibody (aa332-361, FITC) - LS-C214172 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FDFT1 / Squalene Synthase Antibody (aa332-361, Azide-free, HRP) - LS-C214173 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FDFT1 / Squalene Synthase Antibody (aa332-361, PE) - LS-C214174 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FDFT1 / Squalene Synthase Antibody (Internal, AP) - LS-C219261 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FDFT1 / Squalene Synthase Antibody (Internal, APC) - LS-C219262 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FDFT1 / Squalene Synthase Antibody (Internal, Biotin) - LS-C219263 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FDFT1 / Squalene Synthase Antibody (Internal, Azide-free, HRP) - LS-C219265 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FDFT1 / Squalene Synthase Antibody (Internal, FITC) - LS-C219264 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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