| Gene Symbol |
NCOA5
|
| Entrez Gene |
57727
|
| Alt Symbol |
CIA, bA465L10.6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nuclear receptor coactivator 5
|
| Other Description |
NCoA-5|coactivator independent of AF-2
|
| Swissprots |
Q9HCD5 Q9H4Y9 E1P5R0 Q6HA99 Q9H2T2 B2RTV9 Q9H1F2
|
| Accessions |
CAJ42777 EAW75764 EAW75765 EAW75766 EAW75767 EAW75768 EAW75769 EAW75770 Q9HCD5 AB046857 BAB13463 AF230533 AAG36793 AF470686 AAO33457 BC056872 BC140836 AAI40837 BC151133 AAI51134 CN369226 XM_005260474 XP_005260531 XM_011528951 XP_011527253 NM_020967 NP_066018
|
| Function |
Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2). {ECO:0000269|PubMed:15073177}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Widely expressed.
|