Sgpl1

Gene Symbol Sgpl1
Entrez Gene 20397
Alt Symbol AI428538, D10Xrf456, S1PL, Spl
Species Mouse
Gene Type protein-coding
Description sphingosine phosphate lyase 1
Other Description SP-lyase 1|SPL 1|mSPL|sphingosine-1-phosphate aldolase|sphingosine-1-phosphate lyase 1
Swissprots Q8R0X7 O54955 Q8C942
Accessions EDL32155 EDL32156 EDL32157 EDL32158 EDL32159 Q8R0X7 AF036894 AAC03768 AI428538 AK036747 BAC29562 AK037789 BAC29872 AK043024 BAC31437 AK049342 BAC33695 AK075851 AK150053 BAE29269 AK173137 BAD32415 AK180858 AK190149 AK191088 AK192177 AK192450 AK193418 AK193544 AK195290 AK196230 AK196336 AK197017 AK197939 AK199228 AK202302 AK204326 AK208741 AK209049 AK209156 AK209672 AK210156 AK218018 BC026135 AAH26135 BY061956 BY075752 CT010214 CAJ18422 XM_006513402 XP_006513465 XM_006513403 XP_006513466 NM_009163 NP_033189
Function Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. {ECO:0000269|PubMed:9464245}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
Tissue Specificity Highest levels are found in liver, followed by kidney, lung, heart and brain. {ECO:0000269|PubMed:9464245}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

SP-lyase CRISPR/Cas9 KO Plasmid (m) - sc-422908 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SP-lyase HDR Plasmid (m) - sc-422908-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SP-lyase Double Nickase Plasmid (m) - sc-422908-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SP-lyase Double Nickase Plasmid (m2) - sc-422908-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SP-lyase CRISPR Activation Plasmid (m) - sc-422908-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SP-lyase CRISPR Activation Plasmid (m2) - sc-422908-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SP-lyase Lentiviral Activation Particles (m) - sc-422908-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SP-lyase Lentiviral Activation Particles (m2) - sc-422908-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SP-lyase siRNA (m) - sc-72292 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

SP-lyase shRNA Plasmid (m) - sc-72292-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

SP-lyase shRNA (m) Lentiviral Particles - sc-72292-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU048081 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN41084 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND41084 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SGPL1 siRNA (Mouse) - CRM3692 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

SGPL1 - MBS8219360 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse Sgpl1 (NM_009163.3) - SHH406356 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse SGPL1 siRNA - orb283168 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

SGPL1 shRNA Plasmid (Mouse) - CHM3692 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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