Irak2

Gene Symbol Irak2
Entrez Gene 108960
Alt Symbol 6330415L08Rik, AI649099, IRAK-2
Species Mouse
Gene Type protein-coding
Description interleukin-1 receptor-associated kinase 2
Other Description interleukin-1 receptor-associated kinase 2c|interleukin-1 receptor-associated kinase-like 2|mu-IRAK-2
Swissprots Q6YBS1 Q8CFA1 Q6YBS0 Q3UFX2 Q6YBR9 Q3U7F5 Q6YBR8 Q8CEA0 Q8CC82 Q3U3K2 Q8C5M0 Q5U404
Accessions EDK99493 Q8CFA1 AJ440756 CAD29447 AK028733 BAC26088 AK033707 BAC28438 AK078062 BAC37114 AK148248 BAE28437 AK150056 BAE29271 AK151428 BAE30392 AK152682 BAE31414 AK154715 BAE32783 AY162378 AAO24761 AY162379 AAO24762 AY162380 AAO24763 AY162381 AAO24764 BC085324 AAH85324 BY110939 CJ212338 XM_006505325 XP_006505388 NM_001113553 NP_001107025 NM_172161 NP_751893
Function Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. {ECO:0000250}.
Tissue Specificity Ubiquitously expressed, with a higher expression observed in brain, spleen and liver. Isoform 1 and isoform 2 are considered agonist and isoform 3 and isoform 4 are considered antagonist.
Top Pathways Apoptosis, Neurotrophin signaling pathway, Tuberculosis

IRAK-2 CRISPR/Cas9 KO Plasmid (m) - sc-430883 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IRAK-2 HDR Plasmid (m) - sc-430883-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IRAK-2 Double Nickase Plasmid (m) - sc-430883-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IRAK-2 Double Nickase Plasmid (m2) - sc-430883-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IRAK-2 CRISPR Activation Plasmid (m) - sc-430883-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IRAK-2 CRISPR Activation Plasmid (m2) - sc-430883-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IRAK-2 Lentiviral Activation Particles (m) - sc-430883-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IRAK-2 Lentiviral Activation Particles (m2) - sc-430883-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IRAK-2 siRNA (m) - sc-146281 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

IRAK-2 shRNA Plasmid (m) - sc-146281-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

IRAK-2 shRNA (m) Lentiviral Particles - sc-146281-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU026771 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN33928 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33928 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IRAK2 siRNA (Mouse) - CRN0981 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

IRAK2 - MBS8231548 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse IRAK2 (NM_172161.4) - SHH320513 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Irak2(NM_172161.4) - SHL173168 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Irak2(NM_001113553.1) - SHL173334 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse IRAK2 siRNA - orb290456 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

IRAK2 shRNA Plasmid (Mouse) - CHN0981 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

IRAK2 miRNA 3'UTR clone - MiUTR1M-06092 from Creative biogene

Species Reactivities Mouse

IRAK2 miRNA 3'UTR clone - MiUTR1M-06093 from Creative biogene

Species Reactivities Mouse
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