| Gene Symbol |
Htr5b
|
| Entrez Gene |
15564
|
| Alt Symbol |
5-Ht5b
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
5-hydroxytryptamine (serotonin) receptor 5B
|
| Other Description |
5-HT-5B|5-hydroxytryptamine receptor 5B|protein-tyrosine-phosphatase (EC 3.1.3.48) Ly-5 precursor (B-cell variant)|serotonin receptor 5B
|
| Swissprots |
P31387 Q1RME2
|
| Accessions |
EDL39785 P31387 BC114988 AAI14989 BC115825 AAI15826 X69867 CAA49501 XR_878315 NM_010483 NP_034613
|
| Function |
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. Probably involved in anxiety and depression.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed predominantly in the central nervous system; in the hippocampus, habenula, and the doral raphe.
|
| Top Pathways |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|