Gene Symbol | Htr5b |
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Entrez Gene | 15564 |
Alt Symbol | 5-Ht5b |
Species | Mouse |
Gene Type | protein-coding |
Description | 5-hydroxytryptamine (serotonin) receptor 5B |
Other Description | 5-HT-5B|5-hydroxytryptamine receptor 5B|protein-tyrosine-phosphatase (EC 3.1.3.48) Ly-5 precursor (B-cell variant)|serotonin receptor 5B |
Swissprots | P31387 Q1RME2 |
Accessions | EDL39785 P31387 BC114988 AAI14989 BC115825 AAI15826 X69867 CAA49501 XR_878315 NM_010483 NP_034613 |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. Probably involved in anxiety and depression. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed predominantly in the central nervous system; in the hippocampus, habenula, and the doral raphe. |
Top Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
SR-5B CRISPR/Cas9 KO Plasmid (m) - sc-420999 from Santa Cruz Biotechnology
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SR-5B HDR Plasmid (m) - sc-420999-HDR from Santa Cruz Biotechnology
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SR-5B Double Nickase Plasmid (m) - sc-420999-NIC from Santa Cruz Biotechnology
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SR-5B Double Nickase Plasmid (m2) - sc-420999-NIC-2 from Santa Cruz Biotechnology
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SR-5B CRISPR Activation Plasmid (m) - sc-420999-ACT from Santa Cruz Biotechnology
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SR-5B CRISPR Activation Plasmid (m2) - sc-420999-ACT-2 from Santa Cruz Biotechnology
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SR-5B Lentiviral Activation Particles (m) - sc-420999-LAC from Santa Cruz Biotechnology
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SR-5B Lentiviral Activation Particles (m2) - sc-420999-LAC-2 from Santa Cruz Biotechnology
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SR-5B siRNA (m) - sc-42243 from Santa Cruz Biotechnology
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SR-5B shRNA Plasmid (m) - sc-42243-SH from Santa Cruz Biotechnology
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SR-5B shRNA (m) Lentiviral Particles - sc-42243-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN33555 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33555 from Sigma-Aldrich
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shRNA set against Mouse Htr5b (NM_010483.3) - SHH316009 from Creative biogene
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shRNA set against Mouse Htr5b(NM_010483.3) - SHH136181 from Creative biogene
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HTR5B miRNA 3'UTR clone - MiUTR1M-05852 from Creative biogene
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